| Long name: |
PSAP Primary Polyclonal Antibody |
| Also known as: |
PSAP PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
PSAP |
| Specificity: |
This is a highly specific antibody against PSAP |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PSAP |
| Gene ID number: |
5660 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
B, C, Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites, Mutations in PSAP gene have been associated with Gaucher disease, Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups, Tay-Sachs disease, The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities, and D, and metachromatic leukodystrophy, which are similar to each other and are sphingolipid hydrolase activator proteins, PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CSAct, Cerebroside sulfate activator, Co-beta-glucosidase, Component C, Dispersin, GLBA, Glucosylceramidase activator, PSAP, Proactivator polypeptide, Proactivator polypeptide precursor, Prosaposin sphingolipid activator protein 1, Protein A, Protein C, SAP-1, SAP-2, SAP1, SAP_HUMAN, Saposin A, Saposin B, Saposin B Val, Saposin C, Saposin-D, Saposins, Sphingolipid activator protein 1, Sphingolipid activator protein 2, Sulfated glycoprotein 1, Sulfatide/GM1 activator, prosaposin variant Gaucher disease and variant metachromatic leukodystrophy, A1 activator |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
PSAP |
| Short name: |
PSAP Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
PSAP (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
9498 |
| Gene: |
PSAP |
More about : PSAP |
| Long gene name: |
prosaposin |
| Synonyms gene: |
SAP1 GLBA |
| Synonyms gene name: |
sphingolipid activator protein-1 |
| Synonyms name: |
variant Gaucher disease and variant metachromatic leukodystrophy |
| Locus: |
10q22, 1 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
BC004275 |
| Entrez gene record: |
5660 |
| Pubmed identfication: |
2717620 |
| RefSeq identity: |
NM_002778 |
| Classification: |
Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000018429 |