| Long name: |
CXCR3 Primary Polyclonal Antibody |
| Also known as: |
CXCR3 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CXCR3/CD183 |
| Specificity: |
This is a highly specific antibody against CXCR3/CD183 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
330-367/367 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from mouse CXCR3 |
| Gene ID number: |
12766 |
| Swiss Prot: |
O88410 |
| Tested Applications: |
FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Binds to CCL21, CXCL1 and CXCL11 and mediates the proliferation, Probably promotes cell chemotaxis response (By similarity), survival and angiogenic activity of mesangial cells through a heterotrimeric G-protein signaling pathway, Receptor for the C-X-C chemokine CXCL9 |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
C-X-C chemokine receptor type 3, CXC-R3, CXCR-3, Cmkar3, Cxcr3, IP-1 receptor, Interferon-inducible protein 1 receptor, Cd183 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CXCR3 |
| Short name: |
CXCR3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
chemokine (C-X-C motif) receptor 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
C-X-C chemokine binding, CD182 and CD183 and CKR-L2 and CMKAR3 and GPR9 and IP10-R and Mig-R and MigR, CXCR3 and IDBG-635748 and ENSBTAG00000014798 and 497018, CXCR3 and IDBG-76333 and ENSG00000186810 and 2833, Cell surfaces, Cxcr3 and IDBG-164788 and ENSMUSG00000050232 and 12766, this GO :0001525 and angiogenesis and biological process this GO :0001937 and negative regulation of endothelial cell proliferation and biological process this GO :0002685 and regulation of leukocyte migration and biological process this GO :0004872 and receptor activity and molecular function this GO :0004930 and G-protein coupled receptor activity and molecular function this GO :0004950 and chemokine receptor activity and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006928 and cellular component movement and biological process this GO :0006935 and chemotaxis and biological process this GO :0006954 and inflammatory response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007204 and positive regulation of cytosolic calcium ion concentration and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010818 and T cell chemotaxis and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016494 and C-X-C chemokine receptor activity and molecular function this GO :0016525 and negative regulation of angiogenesis and biological process this GO :0019722 and calcium-mediated signaling and biological process this GO :0019956 and chemokine binding and molecular function this GO :0019958 and C-X-C chemokine binding and molecular function this GO :0030816 and positive regulation of cAMP metabolic process and biological process this GO :0043950 and positive regulation of cAMP-mediated signaling and biological process this GO :0045087 and innate immune response and biological process this GO :0045766 and positive regulation of angiogenesis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0050921 and positive regulation of chemotaxis and biological process this GO :0051281 and positive regulation of release of sequestered calcium ion into cytosol and biological process this GO :0071954 and chemokine (C-C motif) ligand 11 production and biological process this GO :1900118 and negative regulation of execution phase of apoptosis and biological process this GO :1900119 and positive regulation of execution phase of apoptosis and biological process, this GO :0004872 : receptor activity, this GO :0004872 : receptor activity and also this GO :0004930 : G-protein coupled receptor activity and also this GO :0004950 : chemokine receptor activity and also this GO :0016494 : C-X-C chemokine receptor activity and also this GO :0019956 : chemokine binding and also this GO :0019958 : C-X-C chemokine binding, this GO :0004930 : G-protein coupled receptor activity, this GO :0004950 : chemokine receptor activity, this GO :0016494 : C-X-C chemokine receptor activity, this GO :0019956 : chemokine binding, this GO :0019958 : C-X-C chemokine binding, chemokine (C-X-C motif) receptor 3 |
| Identity: |
4540 |
| Gene: |
CXCR3 |
More about : CXCR3 |
| Long gene name: |
C-X-C motif chemokine receptor 3 |
| Synonyms gene: |
GPR9 |
| Synonyms gene name: |
G protein-coupled receptor 9 chemokine (C-X-C motif) receptor 3 |
| Synonyms: |
CKR-L2 CMKAR3 IP10-R MigR CD183 |
| Locus: |
Xq13, 1 |
| Discovery year: |
1994-11-01 |
| GenBank acession: |
U32674 |
| Entrez gene record: |
2833 |
| Pubmed identfication: |
8666380 9064356 |
| Classification: |
CD molecules C-X-C motif chemokine receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000033326 |