| Long name: |
ALEXA FLUOR 488 Conjugated, Uromodulin Polyclonal Antibody |
| Also known as: |
Anti-Uromodulin PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Uromodulin |
| Specificity: |
This is a highly specific antibody against Uromodulin |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
375-420/642 |
| Source: |
KLH conjugated synthetic peptide derived from mouse Uromodulin |
| Gene ID Number: |
22242 |
| Swiss Prot: |
Q91X17 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Facilitates neutrophil migration across renal epithelial (By similarity), IL-2) and TNF, Into the urine, May serve as a receptor for binding and endocytosis for cytokines (IL-1, Uromodulin, may contribute to colloid osmotic pressure, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals, retards passage of positively charged electrolytes, secreted form: Secreted into urine after proteolytically cleaveage, where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability, Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Uromodulin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Uromodulin |
| Short name: |
Uromodulin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Uromodulin (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12559 |
| Gene: |
UMOD |
More about : UMOD |
| Long gene name: |
uromodulin |
| Synonyms gene name: |
Tamm-Horsfall glycoprotein) , uromodulin (uromucoid |
| Synonyms name: |
Tamm-Horsfall glycoprotein uromucoid |
| Locus: |
16p12, 3 |
| Discovery year: |
1992-07-27 |
| GenBank acession: |
M17778 |
| Entrez gene record: |
7369 |
| Pubmed identfication: |
8382593 |
| Havana BLAST/BLAT: |
OTTHUMG00000131488 |