| Long name: |
Cy5, 5 Conjugated, Estrogen Receptor alpha Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Cy5, 5, 5, Cy5 |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Estrogen Receptor alpha |
| Specificity: |
This is a highly specific antibody against Estrogen Receptor alpha |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
KLH conjugated synthetic peptide derived from human Estrogen Receptor alpha |
| Gene ID number: |
2099 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
ER Alpha and ER Beta, ER Alpha and ER Beta have been shown to be differentially activated by various ligands, In most cells, The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B), The carboxy terminal region of the estrgen receptor contains the ligand binding domain, The interaction of hormone-bound estrogen receptors with estrogen responsive elements(EREs) alters transcription of ERE-containing genes, Two forms of estrogen receptor have been identified, and the DNA binding domain is centrally located, hPR-B functions as a transcriptional activator of progesterone-responsive gene, the amino terminus serves as the transactivation domain, whereas hPR-A function as a transcriptional inhibitor of all steroid hormone receptors, which arise from alternative splicing, Estrogen and progesterone receptor are members of a family of transcription factors that are regulated by the binding of their cognate ligands |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
675nm/694nm |
| Synonyms: |
Atherosclerosis, DKFZp686N23123, ER, ER Alpha, ER-alpha, ER[a], ERalpha, ESR, ESR1, ESR1_HUMAN, ESR2, ESRA, Era, Estr, Estradiol Receptor-alpha, Estrogen Receptor 1, Estrogen receptor 1 alpha, Estrogen receptor alpha, Estrogen resistance, HDL cholesterol, Myocardial infarction, NR3A1, Nuclear receptor subfamily 3 group A member 1, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR, augmented response of, included, included, included, included, susceptibility to, susceptibility to, to hormone replacement, Estradiol receptor |
| Properties: |
Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated: |
These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target: |
Estrogen Receptor alpha Conjugated |
| Short name: |
Conjugated, Estrogen Receptor alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
5, Cy5 |
| Alternative name: |
cyanine 5, 5 coupled, Estrogen Receptor a (Antibody to) |
| Alternative technique: |
antibodies |