| Long name: |
ALEXA FLUOR 488 Conjugated, Integrin alpha 3 Polyclonal Antibody |
| Also known as: |
Anti-Integrin alpha 3 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Integrin alpha 3 |
| Specificity: |
This is a highly specific antibody against Integrin alpha 3 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1000-1050/1050 |
| Subcellular location: |
Transmembrane |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin alpha 3 |
| Gene ID Number: |
3675 |
| Swiss Prot: |
P26006 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration, Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, collagen, epiligrin, formation of invadopodia and matrix degradation processes, laminin, promoting cell invasion, thrombospondin and CSPG4, Integrin alpha-3/beta-1 is a receptor for fibronectin |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CD49c VLA3a VCA-2 GAP-B3 |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Integrin alpha 3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Integrin alpha 3 |
| Short name: |
Integrin alpha 3 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Integrin a 3 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6139 |
| Gene: |
ITGA3 |
More about : ITGA3 |
| Long gene name: |
integrin subunit alpha 3 |
| Synonyms gene: |
MSK18 |
| Synonyms gene name: |
alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) , antigen identified by monoclonal antibody J143 integrin |
| Synonyms name: |
alpha 3 subunit of VLA-3 receptor antigen CD49C |
| Locus: |
17q21, 33 |
| Discovery year: |
1992-02-27 |
| GenBank acession: |
M59911 |
| Entrez gene record: |
3675 |
| Pubmed identfication: |
1655803 9704023 |
| RefSeq identity: |
NM_005501 |
| Classification: |
Integrin alpha subunits CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000161890 |