| Long name: |
ALEXA FLUOR 647 Conjugated, LAMP-1 Polyclonal Antibody |
| Also known as: |
Anti-LAMP-1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
LAMP-1 |
| Specificity: |
This is a highly specific antibody against LAMP-1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
300-350/417 |
| Subcellular location: |
Lysosome, Lumenal |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LAMP-1 |
| Gene ID Number: |
3916 |
| Swiss Prot: |
P11279 |
| Tested applications: |
IF(IHC-P), FCM |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI), Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1, This mutant protein then cycles between the plasma membrane and the endosome, Upon cell activation, also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation, Lysosome associated membrane protein (LAMP1) |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
CD17 antigen-like family member A, CD17a, LAMP-1, LAMP1, LGP12, Lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1, LAMPA |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the LAMP-1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
LAMP-1 |
| Short name: |
LAMP-1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, LAMP-1 (Antibody to) |
| Alternative technique: |
antibodies |