| Long name: |
Biotin Conjugated, VEGF-A Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
VEGF-A |
| Specificity: |
This is a highly specific antibody against VEGF-A |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
120-170/232 |
| Subcellular location: |
Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human VEGFA |
| Gene ID number: |
7422 |
| Swiss Prot: |
P15692 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, Induces endothelial cell proliferation, Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145, does not activate angiogenesis and inhibits tumor growth, heparan sulfate and heparin, inhibits apoptosis and induces permeabilization of blood vessels, promotes cell migration, vasculogenesis and endothelial cell growth, Growth factor active in angiogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
VEGF-A VPF |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
VEGF-A Conjugated |
| Short name: |
Conjugated, VEGF-A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, VEGF-A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12680 |
| Gene: |
VEGFA |
More about : VEGFA |
| Long gene name: |
vascular endothelial growth factor A |
| Synonyms gene: |
VEGF |
| Synonyms gene name: |
vascular endothelial growth factor |
| Locus: |
6p21, 1 |
| Discovery year: |
1994-01-10 |
| GenBank acession: |
AB021221 |
| Entrez gene record: |
7422 |
| Pubmed identfication: |
8786112 |
| RefSeq identity: |
NM_001025366 |
| Classification: |
VEGF family |
| Havana BLAST/BLAT: |
OTTHUMG00000014745 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |