| Long name: |
WEE1 Primary Polyclonal Antibody |
| Also known as: |
WEE1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
WEE1 |
| Specificity: |
This is a highly specific antibody against WEE1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
570-615/646 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human WEE1 |
| Gene ID number: |
7465 |
| Swiss Prot: |
P30291 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
A correlated decrease in protein level occurs at M/G1 phase, Its activity increases during S and G2 phases and decreases at M phase when it is hyperphosphorylated, Phosphorylation of cyclin B1-CDK1 occurs exclusively on 'Tyr-15' and phosphorylation of monomeric CDK1 does not occur, Specifically phosphorylates and inactivates cyclin B1-complexed CDK1 reaching a maximum during G2 phase and a minimum as cells enter M phase, probably due to its degradation, Acts as a negative regulator of entry into mitosis (G2 to M transition) by protecting the nucleus from cytoplasmically activated cyclin B1-complexed CDK1 before the onset of mitosis by mediating phosphorylation of CDK1 on 'Tyr-15' |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
WEE1, WEE1hu, Wee1-like protein kinase, Wee1A kinase, WEE1A |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
WEE1 |
| Short name: |
WEE1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
WEE1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12761 |
| Gene: |
WEE1 |
More about : WEE1 |
| Long gene name: |
WEE1 G2 checkpoint kinase |
| Synonyms gene name: |
pombe) , pombe) homolog WEE1 homolog (S, wee1+ (S |
| Synonyms: |
WEE1A |
| Locus: |
11p15, 4 |
| Discovery year: |
1992-08-06 |
| GenBank acession: |
X62048 |
| Entrez gene record: |
7465 |
| Pubmed identfication: |
1840647 |
| RefSeq identity: |
NM_003390 |
| Havana BLAST/BLAT: |
OTTHUMG00000165863 |