ZAP70 Antibody, Biotin Conjugated

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Catalog number: bs-1942R-Biotin
Price: 333 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: ZAP70 Antibody, Biotin Conjugated
Quantity: 0.1ml
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Long name: Biotin Conjugated, ZAP70 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Biotinylated
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: ZAP70
Specificity: This is a highly specific antibody against ZAP70
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Source: KLH conjugated synthetic peptide derived from human ZAP-70
Gene ID number: 7535
Tested applications: IHC-P, WB
Recommended dilutions: IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity: Mouse, Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Jul 2008], Lck and Fyn, Mutations in this gene cause selective T-cell defect, This enzyme, This enzyme is also essential for thymocyte development, Two transcript variants that encode different isoforms have been found for this gene, [provided by RefSeq, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells, and it plays a role in T-cell development and lymphocyte activation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, This gene encodes an enzyme belonging to the protein tyrosine kinase family
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Synonyms: ZAP-70 STD
Properties: Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: ZAP70 Conjugated
Short name: Conjugated, ZAP70 Antibody
Technique: antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: Biotin
Alternative name: biotinilated coupled, zeta-chain (TCR) associated protein kinase 70kDa (Antibody to)
Alternative technique: antibodies
Alternative to gene target: Cell surfaces, SRK and STCD and STD and TZK and ZAP-70, ZAP70 and IDBG-62509 and ENSG00000115085 and 7535, ZAP70 and IDBG-629842 and ENSBTAG00000005892 and 504509, Zap70 and IDBG-145089 and ENSMUSG00000026117 and 22637, this GO :0001772 and immunological synapse and cellular component this GO :0001784 and phosphotyrosine binding and molecular function this GO :0002250 and adaptive immune response and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004715 and non-membrane spanning protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006955 and immune response and biological process this GO :0016772 and transferase activity, this GO :0001784 : phosphotyrosine binding, this GO :0001784 : phosphotyrosine binding and also this GO :0004672 : protein kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0004715 : non-membrane spanning protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016772 : transferase activity, this GO :0004672 : protein kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0004715 : non-membrane spanning protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016772 : transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0042101 and T cell receptor complex and cellular component this GO :0042110 and T cell activation and biological process this GO :0042113 and B cell activation and biological process this GO :0043366 and beta selection and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045061 and thymic T cell selection and biological process this GO :0045121 and membrane raft and cellular component this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0046638 and positive regulation of alpha-beta T cell differentiation and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0050850 and positive regulation of calcium-mediated signaling and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0070489 and T cell aggregation and biological process this GO :0072678 and T cell migration and biological process, zeta-chain (TCR) associated protein kinase 70kDa
Identity: 12858
Gene: ZAP70 | More about : ZAP70
Long gene name: zeta chain of T-cell receptor associated protein kinase 70
Synonyms gene: SRK
Synonyms gene name: zeta-chain (TCR) associated protein kinase (70 kD) zeta-chain (TCR) associated protein kinase 70kDa zeta chain of T cell receptor associated protein kinase 70kDa zeta chain of T cell receptor associated protein kinase 70
Synonyms name: tyrosine-protein kinase ZAP-70
Locus: 2q11, 2
Discovery year: 1995-05-16
GenBank acession: L05148
Entrez gene record: 7535
Pubmed identfication: 1423621
RefSeq identity: NM_001079
Classification: SH2 domain containing
Havana BLAST/BLAT: OTTHUMG00000153060
Locus Specific Databases: ZAP70base: Mutation registry for autosomal recessive ZAP70 immunodeficiency LRG_126

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