| Long name: |
FITC Conjugated, SARA Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Anti-FITC Antibody |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
SARA |
| Specificity: |
This is a highly specific antibody against SARA |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
80-130/1425 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human SARA |
| Gene ID number: |
9372 |
| Swiss Prot: |
O95405 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex, Possibly associated with TGF-beta receptor internalization, Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission: |
494nm/518nm |
| Synonyms: |
SAR1 Sara |
| Properties: |
Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SARA Conjugated |
| Short name: |
FITC Conjugated, SARA Antibody |
| Technique: |
Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
FITC |
| Alternative name: |
fluorecein coupled, SARA (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10534 |
| Gene: |
SAR1A |
More about : SAR1A |
| Long gene name: |
secretion associated Ras related GTPase 1A |
| Synonyms gene: |
SARA1 |
| Synonyms gene name: |
Ras related GTPase 1A , SAR1a gene homolog (S, cerevisiae) 1 SAR1a gene homolog 1 (S, cerevisiae) SAR1 homolog A (S, cerevisiae) secretion associated |
| Locus: |
10q22, 1 |
| Discovery year: |
2000-06-28 |
| Entrez gene record: |
56681 |
| Pubmed identfication: |
10871277 |
| Classification: |
ARF GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000018400 |