TRF2 Antibody, FITC Conjugated

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Catalog number: bs-1922R-FITC
Price: 333 €
Supplier: Bioss Primary Conjugated Antibodies
Product name: TRF2 Antibody, FITC Conjugated
Quantity: 0.1ml
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Long name: FITC Conjugated, TRF2 Polyclonal Antibody
Category: Conjugated Primary Antibodies
Conjugation: Anti-FITC Antibody
Host Organism: Rabbit (Oryctolagus cuniculus)
Target Antigen: TRF2
Specificity: This is a highly specific antibody against TRF2
Modification: Unmodified
Modification site: None
Clonality: Polyclonal
Clone: Polyclonal antibody
Concentration: 1ug per 1ul
Immunogen_range: 350-400/542
Subcellular location: Nucleus
Source: KLH conjugated synthetic peptide derived from human TRF2
Gene ID number: 7014
Swiss Prot: Q15554
Tested applications: IF(IHC-P)
Recommended dilutions: IF(IHC-P)(1:50-200)
Crossreactivity: Rat, Human
Crossreactive species details: not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection, In addition to its telomeric DNA-binding role, Preferentially binds to positive supercoiled DNA, Recruits TERF2IP/RAP1 to telomeres, Required both to recruit DCLRE1B/Apollo to telomeres and activate the exonuclease activity of DCLRE1B/Apollo, Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends, TERF2IP/RAP1 and DCLRE1B/Apollo, TOP2A and TOP2B) needed for telomere replication during fork passage and prevent aberrant telomere topology, Together with DCLRE1B/Apollo, Together with DCLRE1B/Apollo, including the shelterin complex, plays a key role in telomeric loop (T loop) formation by generating 3' single-stranded overhang at the leading end telomeres: T loops have been proposed to protect chromosome ends from degradation and repair, required to control the amount of DNA topoisomerase (TOP1, required to recruit a number of factors and enzymes required for telomere protection, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways, thereby participating in to repressing homology-directed repair (HDR), which can affect telomere length, without its protective activity, Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes
Purification method: This antibody was purified via Protein A
Storage conditions: 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission: 494nm/518nm
Synonyms: TRF2
Properties: Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target: TRF2 Conjugated
Short name: FITC Conjugated, TRF2 Antibody
Technique: Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label: FITC
Alternative name: fluorecein coupled, TRF2 (Antibody to)
Alternative technique: antibodies
Identity: 11729
Gene: TERF2 | More about : TERF2
Long gene name: telomeric repeat binding factor 2
Synonyms gene: TRBF2
Locus: 16q22, 1
Discovery year: 1997-11-20
Entrez gene record: 7014
Pubmed identfication: 9326950 10226653
Classification: Shelterin complex Myb/SANT domain containing
Havana BLAST/BLAT: OTTHUMG00000137566

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