| Long name: |
SCN1A Primary Polyclonal Antibody |
| Also known as: |
SCN1A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
SCN1A |
| Specificity: |
This is a highly specific antibody against SCN1A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SCN1A |
| Gene ID number: |
6323 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Alternative splicing results in multiple transcript variants, The RefSeq Project has decided to create four representative RefSeq records, This gene encodes the large alpha subunit, Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and mutations in this gene have been associated with several epilepsy, and two smaller auxiliary beta subunits, convulsion and migraine disorders, mainly in nerve and muscle, the exact combination of which have not been experimentally confirmed for the full-length transcript, SCN1A is a voltage-gated ion channel essential for the generation and propagation of action potentials |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
EIEE6, FEB3, FEB3A, FHM3, GEFS+2, GEFSP2, HBSC I, HBSCI, MIM 182390, NAC1, Nav 1, RBI, SCN1, SCN1A_HUMAN, SCN2A1, SMEI, Scn1a, Sodium channel protein brain I alpha subunit, Sodium channel protein brain I subunit alpha, Sodium channel protein type 1 subunit alpha, Sodium channel protein type I subunit alpha, Sodium channel voltage gated type 1 alpha subunit, Sodium channel voltage gated type I alpha polypeptide, Voltage-gated sodium channel subunit alpha Nav1, brain sodium channel type I, sodium channel, type I, voltage gated, 1, 1, alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
SCN1A |
| Short name: |
SCN1A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SCN1A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
10585 |
| Gene: |
SCN1A |
More about : SCN1A |
| Long gene name: |
sodium voltage-gated channel alpha subunit 1 |
| Synonyms gene: |
SCN1 FEB3 |
| Synonyms gene name: |
alpha subunit sodium channel, febrile convulsions 3 sodium channel, type I, type I alpha subunit , voltage gated, voltage-gated |
| Synonyms: |
Nav1, 1 GEFSP2 HBSCI NAC1 SMEI |
| Locus: |
2q24, 3 |
| Discovery year: |
1988-11-28 |
| GenBank acession: |
AB093548 |
| Entrez gene record: |
6323 |
| Pubmed identfication: |
8062593 16382098 11823106 |
| RefSeq identity: |
NM_006920 |
| Classification: |
Sodium voltage-gated channel alpha subunits |
| Havana BLAST/BLAT: |
OTTHUMG00000044173 |
| Locus Specific Databases: |
Familial Hemiplegic Migraine (FHM) Variation Database LRG_8 |