| Long name: |
TIEG1/KLF10 Primary Polyclonal Antibody |
| Also known as: |
TIEG1/KLF10 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
TIEG1/KLF10 |
| Specificity: |
This is a highly specific antibody against TIEG1/KLF10 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
423-480/480 |
| Subcellular location: |
Nucleus |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human TIEG1 |
| Gene ID number: |
7071 |
| Swiss Prot: |
Q13118 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
May play a role in the cell cycle regulation, Plays a role in the regulation of the circadian clock, Regulates the circadian expression of genes involved in lipogenesis, Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity), and glycolysis in the liver, binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity, gluconeogenesis, Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3' |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
EGR-alpha, KLF10, Krueppel-like factor 10, TGFB-inducible early growth response protein 1, TIEG, TIEG-1, TIEG1, Transforming growth factor-beta-inducible early growth response protein 1, EGRA |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
TIEG1/KLF10 |
| Short name: |
TIEG1/KLF10 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
TIEG1/Kruppel-like factor 10 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0007267 and cell-cell signaling and biological process this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0030282 and bone mineralization and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0045672 and positive regulation of osteoclast differentiation and biological process this GO :0046872 and metal ion binding and molecular function this GO :1901653 and cellular response to peptide and biological process, EGR-alpha and EGRA and TIEG and TIEG1, KLF10 and IDBG-31363 and ENSG00000155090 and 7071, KLF10 and IDBG-645044 and ENSBTAG00000014396 and 522795, Klf10 and IDBG-136307 and ENSMUSG00000037465 and 21847, metal ion binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001501 and skeletal system development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677 : DNA binding, this GO :0003677 : DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0046872 : metal ion binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0046872 : metal ion binding, Kruppel-like factor 10 |
| Identity: |
11810 |
| Gene: |
KLF10 |
More about : KLF10 |
| Long gene name: |
Kruppel like factor 10 |
| Synonyms gene: |
TIEG |
| Synonyms gene name: |
TGFB inducible early growth response |
| Synonyms: |
EGRA TIEG1 |
| Locus: |
8q22, 3 |
| Discovery year: |
1997-08-28 |
| GenBank acession: |
U21847 |
| Entrez gene record: |
7071 |
| Pubmed identfication: |
8584037 9721211 |
| Classification: |
Kruppel like factors Zinc fingers C2H2-type |
| Havana BLAST/BLAT: |
OTTHUMG00000164735 |
| Locus Specific Databases: |
LRG_758 |