| Long name: |
GCK/Glucokinase Primary Polyclonal Antibody |
| Also known as: |
GCK/Glucokinase PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
GCK/Glucokinase |
| Specificity: |
This is a highly specific antibody against GCK/Glucokinase |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
100-150/465 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GCK |
| Gene ID number: |
2645 |
| Swiss Prot: |
P35557 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Glucokinase has a high Km for glucose, Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage, Pancreatic glucokinase plays an important role in modulating insulin secretion, The role of GCK is to provide G6P for the synthesis of glycogen, and so it is effective only when glucose is abundant, Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
FGQTL3, GCK, GLK, Glucokinase, HHF3, HK IV, HK4, HKIV, HXKP, Hexokinase type IV, Hexokinase-4, Hexokinase-D, LGLK, MODY2, GK |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
GCK/Glucokinase |
| Short name: |
GCK/Glucokinase Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
GCK/Glucokinase (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
4195 |
| Gene: |
GCK |
More about : GCK |
| Long gene name: |
glucokinase |
| Synonyms gene: |
MODY2 |
| Synonyms gene name: |
maturity onset diabetes of the young 2 glucokinase (hexokinase 4) |
| Synonyms: |
HK4 |
| Synonyms name: |
hexokinase 4 |
| Locus: |
7p13 |
| Discovery year: |
1991-06-05 |
| GenBank acession: |
AF041014 |
| Entrez gene record: |
2645 |
| Pubmed identfication: |
1740341 1502186 |
| RefSeq identity: |
NM_000162 |
| Havana BLAST/BLAT: |
OTTHUMG00000022903 |
| Locus Specific Databases: |
Monogenic Diabetes LRG_1074 |