| Long name: |
Biotin Conjugated, Mettl14 Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Mettl14 |
| Specificity: |
This is a highly specific antibody against Mettl14 |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
30-80/456 |
| Subcellular location: |
Nucleus |
| Source: |
KLH conjugated synthetic peptide derived from mouse Mettl14 |
| Gene ID number: |
210529 |
| Swiss Prot: |
Q3UIK4 |
| Tested applications: |
WB |
| Recommended dilutions: |
WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop (By similarity), N6-methyladenosine (m6A), m6A methylation of mRNAs encoding key naive pluripotency-promoting transcripts results in transcript destabilization (PubMed:24394384), plays a role in the efficiency of mRNA splicing, processing and mRNA stability, which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and differentiation of embryonic stem cells |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
G430022H21Rik, Kiaa1627, Methyltransferase-like protein 14, Mettl14, N6-adenosine-methyltransferase subunit METTL14, mKIAA1627 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Mettl14 Conjugated |
| Short name: |
Conjugated, Mettl14 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, methyltransferase like 14 (Antibody to) |
| Alternative technique: |
antibodies |