| Catalog number: | bs-1733R-A350 |
|---|---|
| Price: | 350 € |
| Supplier: | Bioss Primary Conjugated Antibodies. |
| Product name: | phospho Met/C-Met(Tyr1365) Antibody, ALEXA FLUOR 350 |
| Quantity: | 100ul |
| Related search: |
| Long name: | ALEXA FLUOR 350 Conjugated, phospho Met/C-Met(Tyr1365) Antibody |
|---|---|
| Also known as: | Anti-c-Met Tyr1365 PAb ALEXA FLUOR 350 |
| Category: | Conjugated Primary Antibodies |
| Conjugated with: | 350, ALEXA FLUOR® |
| Host Organism: | Rabbit (Oryctolagus cuniculus) |
| Target Antigen: | c-Met Tyr1365 |
| Specificity: | This is a highly specific antibody against c-Met Tyr1365 |
| Modification: | Phosphorylation |
| Modification Site: | Tyr1365 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal antibody |
| Concentration: | 1ug per 1ul |
| Immunogen range: | 1345-1385/1390 |
| Subcellular location: | Cytoplasm |
| Source: | KLH conjugated synthetic phosphopeptide derived from human C-Met around the phosphorylation site of Tyr1365 |
| Gene ID Number: | 4233 |
| Swiss Prot: | P08581 |
| Tested applications: | IF(IHC-P) |
| Recommended dilutions: | IF(IHC-P)(1:50-200) |
| Crossreactivity: | Mouse, Rat, Human |
| Cross-reactive species details: | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: | Acts as a receptor for Listeria internalin inlB, During embryonic development, Following activation by ligand, GRB2, In adults, Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules, MET signaling plays a role in gastrulation, PI3 kinase-AKT, PLCG1, Promotes also differentiation and proliferation of hematopoietic cells, Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, Regulates many physiological processes including proliferation, SRC, STAT3 or the adapter GAB1, The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects, angiogenesis and kidney formation, development and migration of muscles and neuronal precursors, interacts with the PI3-kinase subunit PIK3R1, mediating entry of the pathogen into cells, morphogenesis and survival, or PLCgamma-PKC, participates in wound healing as well as organ regeneration and tissue remodeling, scattering, Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand |
| Purification: | Purified by Protein A |
| Storage conditions: | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: | 343nm/442nm |
| Synonyms: | AUTS9, HGF receptor, HGF/SF receptor, Hepatocyte growth factor receptor, MET, Proto-oncogene c-Met, RCCP2, SF receptor, Scatter factor receptor, Tyrosine-protein kinase Met, c-Met, HGFR |
| Properties: | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: | ALEXA FLUOR 350, Alexa Fluor |
| Gene target: | phospho Met/C-Met(Tyr1365) |
| Short name: | phospho Met/C-Met(Tyr1365) Antibody |
| Technique: | antibodies against human proteins, antibodies for, Antibody |
| Label: | ALEXA FLUOR 350 |
| Alternative name: | ALEXA FLUOR 350, phosphorilated Met/C-Met(Tyr1365) (Antibody to) |
| Alternative technique: | antibodies |
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| bs-1733R-Cy7 | phospho Met/C-Met(Tyr1365) Antibody, Cy7 Conjugated | 0.1ml | 368 € | Bioss Primary Conjugated Antibodies | human |
| bs-1733R-FITC | phospho Met/C-Met(Tyr1365) Antibody, FITC Conjugated | 0.1ml | 350 € | Bioss Primary Conjugated Antibodies | human |
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| bs-3271R-A555 | Met (c-Met) (Tyr1003) Antibody, ALEXA FLUOR 555 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-3271R-A594 | Met (c-Met) (Tyr1003) Antibody, ALEXA FLUOR 594 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-3271R-A647 | Met (c-Met) (Tyr1003) Antibody, ALEXA FLUOR 647 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-3273R-A488 | Met (c-met) (Tyr1349) Antibody, ALEXA FLUOR 488 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-3273R-A555 | Met (c-met) (Tyr1349) Antibody, ALEXA FLUOR 555 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |
| bs-3273R-A594 | Met (c-met) (Tyr1349) Antibody, ALEXA FLUOR 594 | 100ul | 350 € | Bioss Primary Conjugated Antibodies. | human |