| Long name: |
ALEXA FLUOR 647 Conjugated, ERCC1 Polyclonal Antibody |
| Also known as: |
Anti-ERCC1 PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
ERCC1 |
| Specificity: |
This is a highly specific antibody against ERCC1 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
175-195/297 |
| Subcellular location: |
Helical |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ERCC1 |
| Gene ID Number: |
2067 |
| Swiss Prot: |
P07992 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
Also required for homology-directed repair (HDR) of DNA double-strand breaks, Participates in the processing of anaphase bridge-generating DNA structures, Responsible, and can result in cytokinesis failure, for the first step in the repair of interstrand cross-links (ICL), in conjunction with SLX4, in conjunction with SLX4, which consist in incompletely processed DNA lesions arising during S or G2 phase, Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Synonyms: |
RAD10 |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the ERCC1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
ERCC1 |
| Short name: |
ERCC1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, complementation family 1 (includes overlapping antisense sequence) (Antibody to), excision repair cross-complementing rodent repair deficiency |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
3'-to lesion and biological process this GO :0006296 and nucleotide-excision repair, 5'-to lesion and biological process this GO :0006302 and double-strand break repair and biological process this GO :0006310 and DNA recombination and biological process this GO :0006312 and mitotic recombination and biological process this GO :0006949 and syncytium formation and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007281 and germ cell development and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007584 and response to nutrient and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0009650 and UV protection and biological process this GO :0009744 and response to sucrose stimulus and biological process this GO :0010165 and response to X-ray and biological process this GO :0010259 and multicellular organismal aging and biological process this GO :0017025 and TBP-class protein binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0032205 and negative regulation of telomere maintenance and biological process this GO :0035166 and post-embryonic hemopoiesis and biological process this GO :0035264 and multicellular organism growth and biological process this GO :0036297 and interstrand cross-link repair and biological process this GO :0043566 and structure-specific DNA binding and molecular function this GO :0045190 and isotype switching and biological process this GO :0048468 and cell development and biological process this GO :0048477 and oogenesis and biological process this GO :0048568 and embryonic organ development and biological process this GO :0051276 and chromosome organization and biological process this GO :0090305 and nucleic acid phosphodiester bond hydrolysis and biological process, COFS4 and RAD10 and UV20, DNA damage removal and biological process this GO :0000720 and pyrimidine dimer repair by nucleotide-excision repair and biological process this GO :0000737 and DNA catabolic process, DNA incision, DNA incision, ERCC1 and IDBG-57509 and ENSG00000012061 and 2067, ERCC1 and IDBG-639466 and ENSBTAG00000017355 and 615637, Ercc1 and IDBG-150201 and ENSMUSG00000003549 and 13870, complementation group 1 (includes overlapping antisense sequence), endonucleolytic and biological process this GO :0000784 and nuclear chromosome, nuclei, structure-specific DNA binding, telomeric region and cellular component this GO :0001094 and TFIID-class transcription factor binding and molecular function this GO :0001302 and replicative cell aging and biological process this GO :0003677 and DNA binding and molecular function this GO :0003684 and damaged DNA binding and molecular function this GO :0003697 and single-stranded DNA binding and molecular function this GO :0004519 and endonuclease activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005669 and transcription factor TFIID complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006281 and DNA repair and biological process this GO :0006283 and transcription-coupled nucleotide-excision repair and biological process this GO :0006289 and nucleotide-excision repair and biological process this GO :0006295 and nucleotide-excision repair, this GO :0000014 and single-stranded DNA endodeoxyribonuclease activity and molecular function this GO :0000109 and nucleotide-excision repair complex and cellular component this GO :0000718 and nucleotide-excision repair, this GO :0000014 : single-stranded DNA endodeoxyribonuclease activity, this GO :0000014 : single-stranded DNA endodeoxyribonuclease activity and also this GO :0001094 : TFIID-class transcription factor binding and also this GO :0003677 : DNA binding and also this GO :0003684 : damaged DNA binding and also this GO :0003697 : single-stranded DNA binding and also this GO :0004519 : endonuclease activity and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0017025 : TBP-class protein binding and also this GO :0019904 : protein domain specific binding and also this GO :0043566 : structure-specific DNA binding, this GO :0001094 : TFIID-class transcription factor binding, this GO :0003677 : DNA binding, this GO :0003684 : damaged DNA binding, this GO :0003697 : single-stranded DNA binding, this GO :0004519 : endonuclease activity, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, this GO :0017025 : TBP-class protein binding, this GO :0019904 : protein domain specific binding, this GO :0043566 : structure-specific DNA binding, excision repair cross-complementing rodent repair deficiency |
| Identity: |
3433 |
| Gene: |
ERCC1 |
More about : ERCC1 |
| Long gene name: |
ERCC excision repair 1, endonuclease non-catalytic subunit |
| Synonyms gene name: |
complementation group 1 (includes overlapping antisense sequence) excision repair cross-complementation group 1 , excision repair cross-complementing rodent repair deficiency |
| Locus: |
19q13, 32 |
| Discovery year: |
2001-06-22 |
| Entrez gene record: |
2067 |
| Pubmed identfication: |
6462228 26939044 |
| RefSeq identity: |
NM_001983 |
| Classification: |
ERCC excision repair associated |
| Havana BLAST/BLAT: |
OTTHUMG00000182121 |