| Long name: |
ALEXA FLUOR 647 Conjugated, C-SKI/v-SKI Polyclonal Antibody |
| Also known as: |
Anti-C-SKI/v-SKI PAb ALEXA FLUOR 647 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
647, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
C-SKI/v-SKI |
| Specificity: |
This is a highly specific antibody against C-SKI/v-SKI |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C-SKI |
| Gene ID Number: |
6497 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Mouse, Rat, Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc, SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins, SKI represses Smad-mediated transcriptional activation, SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, The SKI oncoprotein dramatically affects cell growth, and tumor suppressors, and/or survival, differentiation, probably through its action as a transcriptional co-repressor, transforming growth factor beta, SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
650nm/665nm |
| Properties: |
ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the C-SKI/v-SKI Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
ALEXA FLUOR 647, Alexa Fluor |
| Gene target: |
C-SKI/v-SKI |
| Short name: |
C-SKI/v-SKI Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 647 |
| Alternative name: |
ALEXA FLUOR 647, C-v-ski sarcoma viral oncogene homolog (avian)/v-v-ski sarcoma viral oncogene homolog (avian) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
DNA-templated and biological process this GO :0006367 and transcription initiation from RNA polymerase II promoter and biological process this GO :0007179 and transforming growth factor beta receptor signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009948 and anterior/posterior axis specification and biological process this GO :0010467 and gene expression and biological process this GO :0010626 and negative regulation of Schwann cell proliferation and biological process this GO :0014902 and myotube differentiation and biological process this GO :0016604 and nuclear body and cellular component this GO :0016605 and PML body and cellular component this GO :0017053 and transcriptional repressor complex and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0019904 and protein domain specific binding and molecular function this GO :0021772 and olfactory bulb development and biological process this GO :0022011 and myelination in peripheral nervous system and biological process this GO :0030177 and positive regulation of Wnt signaling pathway and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030512 and negative regulation of transforming growth factor beta receptor signaling pathway and biological process this GO :0030514 and negative regulation of BMP signaling pathway and biological process this GO :0031064 and negative regulation of histone deacetylation and biological process this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032926 and negative regulation of activin receptor signaling pathway and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043010 and camera-type eye development and biological process this GO :0043234 and protein complex and cellular component this GO :0043388 and positive regulation of DNA binding and biological process this GO :0043585 and nose morphogenesis and biological process this GO :0045668 and negative regulation of osteoblast differentiation and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046811 and histone deacetylase inhibitor activity and molecular function this GO :0048147 and negative regulation of fibroblast proliferation and biological process this GO :0048593 and camera-type eye morphogenesis and biological process this GO :0048741 and skeletal muscle fiber development and biological process this GO :0048870 and cell motility and biological process this GO :0060021 and palate development and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060325 and face morphogenesis and biological process this GO :0060349 and bone morphogenesis and biological process this GO :0060395 and SMAD protein signal transduction and biological process this GO :0070207 and protein homotrimerization and biological process this GO :0070491 and repressing transcription factor binding and molecular function, SGS and SKV, SKI and IDBG-634866 and ENSBTAG00000038716 and 506127, SKI and IDBG-86169 and ENSG00000157933 and 6497, Ski and IDBG-207475 and ENSMUSG00000029050 and 20481, nuclei, repressing transcription factor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001843 and neural tube closure and biological process this GO :0002089 and lens morphogenesis in camera-type eye and biological process this GO :0003682 and chromatin binding and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0006351 and transcription, this GO :0003682 : chromatin binding, this GO :0003682 : chromatin binding and also this GO :0003714 : transcription corepressor activity and also this GO :0005515 : protein binding and also this GO :0008270 : zinc ion binding and also this GO :0019901 : protein kinase binding and also this GO :0019904 : protein domain specific binding and also this GO :0031625 : ubiquitin protein ligase binding and also this GO :0046332 : SMAD binding and also this GO :0046811 : histone deacetylase inhibitor activity and also this GO :0070491 : repressing transcription factor binding, this GO :0003714 : transcription corepressor activity, this GO :0005515 : protein binding, this GO :0008270 : zinc ion binding, this GO :0019901 : protein kinase binding, this GO :0019904 : protein domain specific binding, this GO :0031625 : ubiquitin protein ligase binding, this GO :0046332 : SMAD binding, this GO :0046811 : histone deacetylase inhibitor activity, this GO :0070491 : repressing transcription factor binding, v-ski sarcoma viral oncogene homolog (avian) |
| Identity: |
10896 |
| Gene: |
SKI |
More about : SKI |
| Long gene name: |
SKI proto-oncogene |
| Synonyms gene name: |
v-ski avian sarcoma viral oncogene homolog |
| Locus: |
1p36, 32 , 33-p36 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
X15218 |
| Entrez gene record: |
6497 |
| Pubmed identfication: |
2762147 |
| RefSeq identity: |
NM_003036 |
| Classification: |
SKI transcriptional corepressors |
| Havana BLAST/BLAT: |
OTTHUMG00000001407 |