| Long name: |
Biotin Conjugated, Cathepsin D/CTSD Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Cathepsin D/CTSD |
| Specificity: |
This is a highly specific antibody against Cathepsin D/CTSD |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
115-141/412 |
| Subcellular location: |
Lysosome, Secreted |
| Source: |
KLH conjugated synthetic peptide derived from human Capsin D |
| Gene ID number: |
1509 |
| Swiss Prot: |
P07339 |
| Tested applications: |
ELISA, IHC-P, WB |
| Recommended dilutions: |
ELISA(1:500-1000), IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease, Acid protease active in intracellular protein breakdown |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Synonyms: |
CLN10 |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene: |
CTSD |
More about : CTSD |
| Gene target: |
Cathepsin D/CTSD Conjugated |
| Short name: |
Conjugated, Cathepsin D/CTSD Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, Cathepsin D/cathepsin D (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CATD and IDBG-645332 and ENSBTAG00000007622 and 282883, CLN10 and CPSD and HEL-S-130P, CTSD and IDBG-19613 and ENSG00000117984 and 1509, Ctsd and IDBG-212523 and ENSMUSG00000007891 and 13033, Extracellular, protein binding, this GO :0004190 and aspartic-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005764 and lysosome and cellular component this GO :0006508 and proteolysis and biological process this GO :0008219 and cell death and biological process this GO :0019886 and antigen processing and presentation of exogenous peptide antigen via MHC class II and biological process this GO :0022617 and extracellular matrix disassembly and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030574 and collagen catabolic process and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0042470 and melanosome and cellular component this GO :0043202 and lysosomal lumen and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0004190 : aspartic-type endopeptidase activity, this GO :0004190 : aspartic-type endopeptidase activity and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, cathepsin D |
| Identity: |
2529 |
| Long gene name: |
cathepsin D |
| Synonyms gene: |
CPSD |
| Synonyms gene name: |
cathepsin D (lysosomal aspartyl protease) |
| Synonyms name: |
ceroid-lipofuscinosis, neuronal 10 |
| Locus: |
11p15, 5 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
M11233 |
| Entrez gene record: |
1509 |
| Pubmed identfication: |
3927292 |
| RefSeq identity: |
NM_001909 |
| Classification: |
Cathepsins |
| Havana BLAST/BLAT: |
OTTHUMG00000044760 |
| Locus Specific Databases: |
NCL Mutations , Neuronal Ceroid Lipofuscinoses |