| Long name: |
MAD1 Primary Polyclonal Antibody |
| Also known as: |
MAD1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
MAD1 |
| Specificity: |
This is a highly specific antibody against MAD1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MAD1 |
| Gene ID number: |
8379 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization, Mad1p becomes hyperphosphorylated upon spindle depolymerization, The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators, spindle microtubules |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
HsMAD1, MAD1L1, MD1L1_HUMAN, Mitotic arrest deficient 1, Mitotic checkpoint MAD1 protein homolog, Mitotic spindle assembly checkpoint protein MAD1, PIG9, TP53I9 , TXBP181, Tax binding protein 181, Tumor protein p53 inducible protein 9, hMAD1, mitosis arrest deficiency 1 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
MAD1 |
| Short name: |
MAD1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
MAD1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
6761 |
| Gene: |
MXD1 |
More about : MXD1 |
| Long gene name: |
MAX dimerization protein 1 |
| Synonyms gene: |
MAD |
| Synonyms: |
MAD1 bHLHc58 |
| Locus: |
2p13, 3 |
| Discovery year: |
1994-02-16 |
| Entrez gene record: |
4084 |
| Pubmed identfication: |
7829091 |
| RefSeq identity: |
NM_002357 |
| Classification: |
Basic helix-loop-helix proteins MAX dimerization proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000129646 |