| Long name: |
Alpha-Catenin/CTNNA1 Primary Polyclonal Antibody |
| Also known as: |
Alpha-Catenin/CTNNA1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Alpha-Catenin/CTNNA1 |
| Specificity: |
This is a highly specific antibody against Alpha-Catenin/CTNNA1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
850-900/906 |
| Subcellular location: |
Cell membrane, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Catenin |
| Gene ID number: |
1495 |
| Swiss Prot: |
P35221 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Can associate with both E- and N-cadherins, In contrast, May play a crucial role in cell differentiation, Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions, The association of catenins to cadherins produces a complex which is linked to the actin filament network, The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments, and which seems to be of primary importance for cadherins cell-adhesion properties, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components, Associates with the cytoplasmic domain of a variety of cadherins |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
Alpha E-catenin, CTNNA1, Cadherin-associated protein, Catenin alpha-1, Renal carcinoma antigen NY-REN-13, CAP102 |
| Description: |
- or alpha protein sometimes glycoprotein present in blood, The Alpha-Catenin/CTNNA1 Antibody is a &alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Alpha-Catenin/CTNNA1 |
| Short name: |
Alpha-Catenin/CTNNA1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
102kDa (Antibody to), a 1, a-Catenin/catenin (cadherin-associated protein) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
102kDa, BT, CAP102, CTNNA1 and IDBG-47369 and ENSG00000044115 and 1495, Cell surfaces, Ctnna1 and IDBG-136630 and ENSMUSG00000037815 and 12385, actin filament binding, alpha 1, this GO :0001541 and ovarian follicle development and biological process this GO :0001669 and acrosomal vesicle and cellular component this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005915 and zonula adherens and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007163 and establishment or maintenance of cell polarity and biological process this GO :0007406 and negative regulation of neuroblast proliferation and biological process this GO :0007568 and aging and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008584 and male this GO nad development and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014704 and intercalated disc and cellular component this GO :0015629 and actin cytoskeleton and cellular component this GO :0016264 and gap junction assembly and biological process this GO :0016342 and catenin complex and cellular component this GO :0017166 and vinculin binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0031103 and axon regeneration and biological process this GO :0034329 and cell junction assembly and biological process this GO :0034332 and adherens junction organization and biological process this GO :0034613 and cellular protein localization and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043297 and apical junction assembly and biological process this GO :0043627 and response to estrogen and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045216 and cell-cell junction organization and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045296 and cadherin binding and molecular function this GO :0045880 and positive regulation of smoothened signaling pathway and biological process this GO :0051015 and actin filament binding and molecular function this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0071681 and cellular response to indole-3-methanol and biological process this GO :0090136 and epithelial cell-cell adhesion and biological process this GO :2000146 and negative regulation of cell motility and biological process this GO :2001045 and negative regulation of integrin-mediated signaling pathway and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :2001241 and positive regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005198 : structural molecule activity, this GO :0005198 : structural molecule activity and also this GO :0005515 : protein binding and also this GO :0008013 : beta-catenin binding and also this GO :0017166 : vinculin binding and also this GO :0044822 : poly(A) RNA binding and also this GO :0045295 : gamma-catenin binding and also this GO :0045296 : cadherin binding and also this GO :0051015 : actin filament binding, this GO :0005515 : protein binding, this GO :0008013 : beta-catenin binding, this GO :0017166 : vinculin binding, this GO :0044822 : poly(A) RNA binding, this GO :0045295 : gamma-catenin binding, this GO :0045296 : cadherin binding, this GO :0051015 : actin filament binding, 63787 and IDBG-645999 and ENSBTAG00000014182 and 526848, catenin (cadherin-associated protein) |
| Identity: |
2509 |
| Gene: |
CTNNA1 |
More about : CTNNA1 |
| Long gene name: |
catenin alpha 1 |
| Synonyms gene name: |
102kDa catenin (cadherin-associated protein), alpha 1, alpha 1 , alpha 1 (102kD) catenin (cadherin-associated protein), catenin (cadherin-associated protein) |
| Synonyms: |
CAP102 |
| Locus: |
5q31, 2 |
| Discovery year: |
1993-07-13 |
| GenBank acession: |
D13866 |
| Entrez gene record: |
1495 |
| Pubmed identfication: |
1924379 |
| RefSeq identity: |
NM_001903 |
| Havana BLAST/BLAT: |
OTTHUMG00000163502 |