| Long name: |
RELN/Reelin Primary Polyclonal Antibody |
| Also known as: |
RELN/Reelin PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
RELN/Reelin |
| Specificity: |
This is a highly specific antibody against RELN/Reelin |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
3320-3370/3458 |
| Subcellular location: |
Secreted, Extracellular |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RELN |
| Gene ID number: |
5649 |
| Swiss Prot: |
P78509 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Affects migration of sympathetic preganglionic neurons in the spinal cord, Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation (By similarity), Enzymatic activity is important for the modulation of cell adhesion, Regulates microtubule function in neurons and neuronal migration, where it seems to act as a barrier to neuronal migration, Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
ETL7, LIS2, PRO1598, RELN, Reelin, RL |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
RELN/Reelin |
| Short name: |
RELN/Reelin Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
reelin/Reelin (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
Extracellular, LIS2 and PRO1598 and RL, RELN and IDBG-34522 and ENSG00000189056 and 5649, RELN and IDBG-631504 and ENSBTAG00000003658 and 281450, Reln and IDBG-138749 and ENSMUSG00000042453 and 19699, glutamatergic and biological process this GO :0061003 and positive regulation of dendritic spine morphogenesis and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :0070325 and lipoprotein particle receptor binding and molecular function this GO :0070326 and very-low-density lipoprotein particle receptor binding and molecular function this GO :0090129 and positive regulation of synapse maturation and biological process this GO :0097114 and N-methyl-D-aspartate receptor clustering and biological process this GO :0097119 and postsynaptic density protein 95 clustering and biological process this GO :0097120 and receptor localization to synapse and biological process this GO :0097477 and lateral motor column neuron migration and biological process this GO :1900273 and positive regulation of long-term synaptic potentiation and biological process this GO :1902078 and positive regulation of lateral motor column neuron migration and biological process this GO :2000310 and regulation of N-methyl-D-aspartate selective glutamate receptor activity and biological process this GO :2000463 and positive regulation of excitatory postsynaptic membrane potential and biological process this GO :2000969 and positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity and biological process, this GO :0000904 and cell morphogenesis involved in differentiation and biological process this GO :0001764 and neuron migration and biological process this GO :0004712 and protein serine/threonine/tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006508 and proteolysis and biological process this GO :0007155 and cell adhesion and biological process this GO :0007411 and axon guidance and biological process this GO :0007417 and central nervous system development and biological process this GO :0007420 and brain development and biological process this GO :0007616 and long-term memory and biological process this GO :0008236 and serine-type peptidase activity and molecular function this GO :0008306 and associative learning and biological process this GO :0010001 and glial cell differentiation and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016358 and dendrite development and biological process this GO :0016477 and cell migration and biological process this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0021511 and spinal cord patterning and biological process this GO :0021517 and ventral spinal cord development and biological process this GO :0021766 and hippocampus development and biological process this GO :0021800 and cerebral cortex tangential migration and biological process this GO :0021819 and layer formation in cerebral cortex and biological process this GO :0021987 and cerebral cortex development and biological process this GO :0030425 and dendrite and cellular component this GO :0030900 and forebrain development and biological process this GO :0032008 and positive regulation of TOR signaling and biological process this GO :0032793 and positive regulation of CREB transcription factor activity and biological process this GO :0035418 and protein localization to synapse and biological process this GO :0038026 and reelin-mediated signaling pathway and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048265 and response to pain and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050795 and regulation of behavior and biological process this GO :0050804 and regulation of synaptic transmission and biological process this GO :0051057 and positive regulation of small GTPase mediated signal transduction and biological process this GO :0051968 and positive regulation of synaptic transmission, this GO :0004712 : protein serine/threonine/tyrosine kinase activity, this GO :0004712 : protein serine/threonine/tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0008236 : serine-type peptidase activity and also this GO :0046872 : metal ion binding and also this GO :0070325 : lipoprotein particle receptor binding and also this GO :0070326 : very-low-density lipoprotein particle receptor binding, this GO :0005515 : protein binding, this GO :0008236 : serine-type peptidase activity, this GO :0046872 : metal ion binding, this GO :0070325 : lipoprotein particle receptor binding, this GO :0070326 : very-low-density lipoprotein particle receptor binding, very-low-density lipoprotein particle receptor binding, reelin |
| Identity: |
9957 |
| Gene: |
RELN |
More about : RELN |
| Long gene name: |
reelin |
| Synonyms: |
RL PRO1598 |
| Locus: |
7q22, 1 |
| Discovery year: |
1997-07-22 |
| Entrez gene record: |
5649 |
| Pubmed identfication: |
9049633 |
| RefSeq identity: |
NM_005045 |
| Havana BLAST/BLAT: |
OTTHUMG00000157247 |