| Long name: |
ALEXA FLUOR 488 Conjugated, Complement C4 Polyclonal Antibody |
| Also known as: |
Anti-Complement C4 PAb ALEXA FLUOR 488 |
| Category: |
Conjugated Primary Antibodies |
| Conjugated with: |
488, ALEXA FLUOR® |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
Complement C4 |
| Specificity: |
This is a highly specific antibody against Complement C4 |
| Modification: |
Unmodified |
| Modification Site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
70-120/1744 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Complement C4 |
| Gene ID Number: |
720721 |
| Swiss Prot: |
P0C0L4 |
| Tested applications: |
IF(IHC-P) |
| Recommended dilutions: |
IF(IHC-P)(1:50-200) |
| Crossreactivity: |
Human |
| Cross-reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen: |
C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, C4a anaphylatoxin is a mediator of local inflammatory process, Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes, Derived from proteolytic degradation of complement C4, It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens, Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway |
| Purification: |
Purified by Protein A |
| Storage conditions: |
50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission: |
499nm/519nm |
| Synonyms: |
CPAMD2 C4S CO4 C4 C4A3 C4A2 C4A4 C4A6 C4B RG |
| Properties: |
ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Complement C4 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Gene target: |
Complement C4 |
| Short name: |
Complement C4 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Label: |
ALEXA FLUOR 488 |
| Alternative name: |
ALEXA FLUOR 488, Complement C4 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
1323 |
| Gene: |
C4A |
More about : C4A |
| Long gene name: |
complement C4A (Rodgers blood group) |
| Synonyms gene name: |
complement component 4A complement component 4A (Rodgers blood group) |
| Locus: |
6p21, 33 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
L26261 M14823 X77491 AY224378 |
| Entrez gene record: |
720 |
| RefSeq identity: |
NM_007293 |
| Classification: |
Complement system Blood group antigens C3 and PZP like, alpha-2-macroglobulin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000031186 |
| Locus Specific Databases: |
LRG_137 |