| Long name: |
NeuroD1 Primary Polyclonal Antibody |
| Also known as: |
NeuroD1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
NeuroD1 |
| Specificity: |
This is a highly specific antibody against NeuroD1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
1-50/356 |
| Subcellular location: |
Nucleus, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NeuroD1 |
| Gene ID number: |
4760 |
| Swiss Prot: |
Q13562 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Also required for dendrite morphogenesis and maintenance in the cerebellar cortex, Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis (By similarity), Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A, Contributes to the regulation of several cell differentiation pathways, Together with PAX6 or SIX3, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, inner ear sensory neurons, is required for the regulation of amacrine cell fate specification, like those that promote the formation of early retinal ganglion cells, Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3' |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BHF-1, Class A basic helix-loop-helix protein 3, MODY6, NEUROD, NeuroD1, Neurogenic differentiation factor 1, bHLHa3, BETA2 |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
NeuroD1 |
| Short name: |
NeuroD1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
neuronal differentiation 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
7762 |
| Gene: |
NEUROD1 |
More about : NEUROD1 |
| Long gene name: |
neuronal differentiation 1 |
| Synonyms gene: |
NEUROD |
| Synonyms gene name: |
neurogenic differentiation 1 |
| Synonyms: |
BETA2 BHF-1 NeuroD bHLHa3 MODY6 |
| Synonyms name: |
beta-cell E-box transactivator 2 neurogenic helix-loop-helix protein NEUROD |
| Locus: |
2q31, 3 |
| Discovery year: |
1996-03-12 |
| GenBank acession: |
U50823 |
| Entrez gene record: |
4760 |
| Pubmed identfication: |
7754368 8786144 |
| RefSeq identity: |
NM_002500 |
| Classification: |
Basic helix-loop-helix proteins |
| Havana BLAST/BLAT: |
OTTHUMG00000132583 |