| Long name: |
CNTF Receptor alpha Primary Polyclonal Antibody |
| Also known as: |
CNTF Receptor alpha PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
CNTF Receptor alpha |
| Specificity: |
This is a highly specific antibody against CNTF Receptor alpha |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
160-210/372 |
| Subcellular location: |
Cell membrane |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CNTFR Alpha |
| Gene ID number: |
1271 |
| Swiss Prot: |
P26992 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Along with LIFR and gp130, Alternative splicing has been observed at this locus and two variants, CNTF Receptor alpha forms the heterotrimeric CNTF receptor complex, CNTF first binds to CNTF Recepror alpha, During signal transduction, Signal transduction stimulates gene expression, The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain, and this permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex, both encoding the same protein, cell survival or differentiation in a variety of neuronal cell types, have been identified, CNTF Receptor alpha is a receptor belonging to the cytokine superfamily of receptors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
CNTF receptor subunit alpha, CNTFR, CNTFR-alpha, Ciliary neurotrophic factor receptor subunit alpha |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
CNTF Receptor alpha |
| Short name: |
CNTF Receptor alpha Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
ciliary neurotrophic factor Receptor a (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CNTF and IDBG-409278 and ENSG00000242689 and 1270, CNTF and IDBG-637978 and ENSBTAG00000003624 and 100848228, Cntf and IDBG-254935 and ENSMUSG00000079415 and 12803, Extracellular, HCNTF, growth factor activity, this GO :0005127 and ciliary neurotrophic factor receptor binding and molecular function this GO :0005138 and interleukin-6 receptor binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0007165 and signal transduction and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0040007 and growth and biological process this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0046533 and negative regulation of photoreceptor cell differentiation and biological process this GO :0046668 and regulation of retinal cell programmed cell death and biological process this GO :0048644 and muscle organ morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0070120 and ciliary neurotrophic factor-mediated signaling pathway and biological process this GO :0097058 and CRLF-CLCF1 complex and cellular component, this GO :0005127 : ciliary neurotrophic factor receptor binding, this GO :0005127 : ciliary neurotrophic factor receptor binding and also this GO :0005138 : interleukin-6 receptor binding and also this GO :0008083 : growth factor activity, this GO :0005138 : interleukin-6 receptor binding, this GO :0008083 : growth factor activity, ciliary neurotrophic factor |
| Identity: |
2169 |
| Gene: |
CNTF |
More about : CNTF |
| Long gene name: |
ciliary neurotrophic factor |
| Synonyms: |
HCNTF |
| Locus: |
11q12, 1 |
| Discovery year: |
1991-01-07 |
| GenBank acession: |
BC068030 |
| Entrez gene record: |
1270 |
| Pubmed identfication: |
1840538 1714745 |
| RefSeq identity: |
NM_000614 |
| Classification: |
Interleukin 6 cytokine family |
| Havana BLAST/BLAT: |
OTTHUMG00000137476 |
| Locus Specific Databases: |
ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database |