| Long name: |
Apollon/BIRC6 Primary Polyclonal Antibody |
| Also known as: |
Apollon/BIRC6 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Apollon/BIRC6 |
| Specificity: |
This is a highly specific antibody against Apollon/BIRC6 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
4765-4805/4857 |
| Subcellular location: |
Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Apollon |
| Gene ID number: |
57448 |
| Swiss Prot: |
Q9NR09 |
| Tested Applications: |
IF(IHC-P), IHC-P |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as an inhibitor of CASP3, CASP7 and CASP9, Crucial for normal vesicle targeting to the site of abscission, Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, Important regulator for the final stages of cytokinesis, Its tragets include CASP9 and DIABLO/SMAC, and its striking ubiquitin modification, but also for the integrity of the midbody and the midbody ring, forming a chimeric E2/E3 ubiquitin ligase, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
APOLLON, BIR repeat-containing ubiquitin-conjugating enzyme, BIRC6, Baculoviral IAP repeat-containing protein 6, KIAA1289, Ubiquitin-conjugating BIR domain enzyme apollon, BRUCE |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Apollon/BIRC6 |
| Short name: |
Apollon/BIRC6 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Apollon/baculoviral IAP repeat containing 6 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BIRC6 and IDBG-43545 and ENSG00000115760 and 57448, BIRC6 and IDBG-632006 and ENSBTAG00000027932 and 534211, Birc6 and IDBG-197962 and ENSMUSG00000024073 and 12211, Plasma membranes, acid-amino acid ligase activity, this GO :0000922 and spindle pole and cellular component this GO :0001890 and placenta development and biological process this GO :0004842 and ubiquitin-protein transferase activity and molecular function this GO :0004869 and cysteine-type endopeptidase inhibitor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005768 and endosome and cellular component this GO :0005802 and trans- this GO lgi network and cellular component this GO :0005815 and microtubule organizing center and cellular component this GO :0006464 and cellular protein modification process and biological process this GO :0006468 and protein phosphorylation and biological process this GO :0006915 and apoptotic process and biological process this GO :0007067 and mitotic nuclear division and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010951 and negative regulation of endopeptidase activity and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016881 and acid-amino acid ligase activity and molecular function this GO :0030496 and midbody and cellular component this GO :0032465 and regulation of cytokinesis and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0060711 and labyrinthine layer development and biological process this GO :0060712 and spongiotrophoblast layer development and biological process this GO :2001237 and negative regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0004842 : ubiquitin-protein transferase activity, this GO :0004842 : ubiquitin-protein transferase activity and also this GO :0004869 : cysteine-type endopeptidase inhibitor activity and also this GO :0005515 : protein binding and also this GO :0016881 : acid-amino acid ligase activity, this GO :0004869 : cysteine-type endopeptidase inhibitor activity, this GO :0005515 : protein binding, this GO :0016881 : acid-amino acid ligase activity, baculoviral IAP repeat containing 6 |
| Identity: |
13516 |
| Gene: |
BIRC6 |
More about : BIRC6 |
| Long gene name: |
baculoviral IAP repeat containing 6 |
| Synonyms gene name: |
baculoviral IAP repeat-containing 6 |
| Synonyms: |
BRUCE |
| Synonyms name: |
apollon |
| Locus: |
2p22, 3 |
| Discovery year: |
2000-09-19 |
| GenBank acession: |
AF265555 |
| Entrez gene record: |
57448 |
| Pubmed identfication: |
10544019 |
| RefSeq identity: |
NM_016252 |
| Classification: |
Baculoviral IAP repeat containing Ubiquitin conjugating enzymes E2 |
| Havana BLAST/BLAT: |
OTTHUMG00000150528 |