| Long name: |
Bim/BCL2L11 Primary Polyclonal Antibody |
| Also known as: |
Bim/BCL2L11 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Bim/BCL2L11 |
| Specificity: |
This is a highly specific antibody against Bim/BCL2L11 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
70-120/198 |
| Subcellular location: |
Mitochondrion, Cytoplasm |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human of human Bim |
| Gene ID number: |
10018 |
| Swiss Prot: |
O43521 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Isoform Bim-alpha1, Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway, Isoform Bim-gamma induces apoptosis, Isoform BimAC and isoform BimABC lack the ability to induce apoptosis, Isoform BimL is more potent than isoform BimEL, although less potent than isoform BimEL, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, isoform BimL and isoform BimS, Induces apoptosis and anoikis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BCL2L11, BIM, BOD, Bcl-2-like protein 11, Bcl2-L-11, Bcl2-interacting mediator of cell death, BAM |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Bim/BCL2L11 |
| Short name: |
Bim/BCL2L11 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Bim/B-cell CLL/lymphoma 2-like 11 (apoptosis facilitator) (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
BAM and BIM and BOD, BCL2L11 and IDBG-628964 and ENSBTAG00000024105 and 507390, BCL2L11 and IDBG-65821 and ENSG00000153094 and 10018, Bcl2l11 and IDBG-205300 and ENSMUSG00000027381 and 12125, Plasma membranes, microtubule binding, this GO :0001701 and in utero embryonic development and biological process this GO :0001776 and leukocyte homeostasis and biological process this GO :0001782 and B cell homeostasis and biological process this GO :0001783 and B cell apoptotic process and biological process this GO :0001822 and kidney development and biological process this GO :0002260 and lymphocyte homeostasis and biological process this GO :0002262 and myeloid cell homeostasis and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0005874 and microtubule and cellular component this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007283 and spermatogenesis and biological process this GO :0007420 and brain development and biological process this GO :0008017 and microtubule binding and molecular function this GO :0008584 and male this GO nad development and biological process this GO :0008630 and intrinsic apoptotic signaling pathway in response to DNA damage and biological process this GO :0009791 and post-embryonic development and biological process this GO :0010942 and positive regulation of cell death and biological process this GO :0012505 and endomembrane system and cellular component this GO :0019898 and extrinsic component of membrane and cellular component this GO :0030879 and mammary gland development and biological process this GO :0032464 and positive regulation of protein homooli this GO merization and biological process this GO :0034976 and response to endoplasmic reticulum stress and biological process this GO :0035148 and tube formation and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043029 and T cell homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0043583 and ear development and biological process this GO :0045787 and positive regulation of cell cycle and biological process this GO :0046620 and regulation of organ growth and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048066 and developmental pigmentation and biological process this GO :0048070 and regulation of developmental pigmentation and biological process this GO :0048536 and spleen development and biological process this GO :0048538 and thymus development and biological process this GO :0048563 and post-embryonic organ morphogenesis and biological process this GO :0060139 and positive regulation of apoptotic process by virus and biological process this GO :0060154 and cellular process regulating host cell cycle in response to virus and biological process this GO :0070242 and thymocyte apoptotic process and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097140 and BIM-BCL-xl complex and cellular component this GO :0097141 and BIM-BCL-2 complex and cellular component this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1902110 and positive regulation of mitochondrial membrane permeability involved in apoptotic process and biological process this GO :1902263 and apoptotic process involved in embryonic digit morphogenesis and biological process this GO :2000271 and positive regulation of fibroblast apoptotic process and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0008017 : microtubule binding, this GO :0008017 : microtubule binding, BCL2-like 11 (apoptosis facilitator) |
| Identity: |
994 |
| Gene: |
BCL2L11 |
More about : BCL2L11 |
| Long gene name: |
BCL2 like 11 |
| Synonyms gene name: |
BCL2-like 11 (apoptosis facilitator) |
| Synonyms: |
BOD BimL BimEL BimS BIM |
| Locus: |
2q13 |
| Discovery year: |
1999-12-10 |
| GenBank acession: |
AF032458 |
| Entrez gene record: |
10018 |
| Pubmed identfication: |
9731710 9430630 |
| Classification: |
BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT: |
OTTHUMG00000131256 |
| Locus Specific Databases: |
LRG_620 |