| Long name: |
BIN1 Primary Polyclonal Antibody |
| Also known as: |
BIN1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
BIN1 |
| Specificity: |
This is a highly specific antibody against BIN1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BIN1 |
| Gene ID number: |
274 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Bin1 (Box-dependent myc interacting protein 1, Bin1 also interacts with HCV NS5A through its SH3 domain, Bin1 interacts with and inhibits the oncogenic activity of the myc oncoprotein that has a major role in many human cancers, The loss of Bin1 may contribute to growth deregulation in cancer cells in carcinoma of the breast, also known as SH3P9, amphiphysin II and amphl/amphiphysin-like) is a novel protein that has features of a tumor suppressor, cervix, colon, lung, prostate and liver, The identification and analysis of tumor suppressors is of major importance for improved diagnosis and treatment of tumors |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
AMPH 2, AMPH2, AMPHL, Amphiphysin 2, Amphiphysin II, Amphiphysin like protein, BIN1_HUMAN, Box Dependant MYC Interacting Protein 1, Bridging Integrator 1, DKFZp547F068, MGC10367, MGC105358, Myc box dependent interacting protein 1, SH3P9, amphiphysin-like, Amphiphysin like protein |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
BIN1 |
| Short name: |
BIN1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
bridging integrator 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
AMPH2 and AMPHL and SH3P9, BIN1 and IDBG-639275 and ENSBTAG00000019177 and 614576, BIN1 and IDBG-68691 and ENSG00000136717 and 274, Bin1 and IDBG-133763 and ENSMUSG00000024381 and 30948, GTPase binding, nuclei, this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006897 and endocytosis and biological process this GO :0008021 and synaptic vesicle and cellular component this GO :0008283 and cell proliferation and biological process this GO :0015629 and actin cytoskeleton and cellular component this GO :0016032 and viral process and biological process this GO :0030018 and Z disc and cellular component this GO :0030315 and T-tubule and cellular component this GO :0030424 and axon and cellular component this GO :0031674 and I band and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0033268 and node of Ranvier and cellular component this GO :0042692 and muscle cell differentiation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043194 and axon initial segment and cellular component this GO :0043196 and varicosity and cellular component this GO :0043547 and positive regulation of GTPase activity and biological process this GO :0043679 and axon terminus and cellular component this GO :0044300 and cerebellar mossy fiber and cellular component this GO :0045664 and regulation of neuron differentiation and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048156 and tau protein binding and molecular function this GO :0048711 and positive regulation of astrocyte differentiation and biological process this GO :0051020 and GTPase binding and molecular function this GO :0060987 and lipid tube and cellular component this GO :0060988 and lipid tube assembly and biological process this GO :0071156 and regulation of cell cycle arrest and biological process, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0032403 : protein complex binding and also this GO :0042802 : identical protein binding and also this GO :0046982 : protein heterodimerization activity and also this GO :0048156 : tau protein binding and also this GO :0051020 : GTPase binding, this GO :0032403 : protein complex binding, this GO :0042802 : identical protein binding, this GO :0046982 : protein heterodimerization activity, this GO :0048156 : tau protein binding, this GO :0051020 : GTPase binding, bridging integrator 1 |
| Identity: |
1052 |
| Gene: |
BIN1 |
More about : BIN1 |
| Long gene name: |
bridging integrator 1 |
| Synonyms gene: |
AMPHL |
| Synonyms: |
SH3P9 AMPH2 |
| Synonyms name: |
amphiphysin II |
| Locus: |
2q14, 3 |
| Discovery year: |
2000-05-19 |
| GenBank acession: |
U68485 |
| Entrez gene record: |
274 |
| Pubmed identfication: |
8725406 8782822 17676042 |
| RefSeq identity: |
NM_139343 |
| Classification: |
N-BAR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131465 |
| Locus Specific Databases: |
LRG_873 |