| Long name: |
Gremlin 1 Primary Polyclonal Antibody |
| Also known as: |
Gremlin 1 PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
Gremlin 1 |
| Specificity: |
This is a highly specific antibody against Gremlin 1 |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen range: |
130-170/184 |
| Subcellular location: |
Secreted |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human gremlin 1 |
| Gene ID number: |
26585 |
| Swiss Prot: |
O60565 |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Acts as inhibitor of monocyte chemotaxis (By similarity), Down-regulates the BMP4 signaling in a dose-dependent manner, as a BMP antagonist required for early limb outgrowth and patterning in maintaining the FGF4-SHH feedback loop, Cytokine that may play an important role during carcinogenesis and metanephric kidney organogenesis |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
BMP antagonist 1, CKTSF1B1, CRAC1, Cell proliferation-inducing gene 2 protein, Cysteine knot superfamily 1, DAN domain family member 2, DAND2, Down-regulated in Mos-transformed cells protein, GREM1, GREMLIN, Gremlin-1, HMPS, IHG-2, Increased in high glucose protein 2, PIG2, DRM |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
Gremlin 1 |
| Short name: |
Gremlin 1 Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
Gremlin 1 (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
20574 |
| Gene: |
CRAC1 |
More about : CRAC1 |
| Long gene name: |
DAN family BMP antagonist , gremlin 1 |
| Synonyms gene: |
CKTSF1B1 |
| Synonyms gene name: |
BMP antagonist 1 gremlin 1, cysteine knot superfamily, cysteine knot superfamily 1, homolog (Xenopus laevis) gremlin 1 colorectal adenoma and carcinoma 1 |
| Synonyms: |
DRM gremlin DAND2 HMPS GREM1 |
| Locus: |
15q13, 3 |
| Discovery year: |
1999-12-02 |
| Entrez gene record: |
26585 |
| Pubmed identfication: |
9660951 10026205 22561515 27385727 |
| RefSeq identity: |
NM_013372 |
| Classification: |
DAN family |
| Havana BLAST/BLAT: |
OTTHUMG00000129319 |