| Long name: |
Biotin Conjugated, EPOR Polyclonal Antibody |
| Category: |
Conjugated Primary Antibodies |
| Conjugation: |
Biotinylated |
| Host Organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Antigen: |
EPOR |
| Specificity: |
This is a highly specific antibody against EPOR |
| Modification: |
Unmodified |
| Modification site: |
None |
| Clonality: |
Polyclonal |
| Clone: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Immunogen_range: |
330-380/508 |
| Subcellular location: |
Cytoplasm |
| Source: |
KLH conjugated synthetic peptide derived from human EPOR |
| Gene ID number: |
2057 |
| Swiss Prot: |
P19235 |
| Tested applications: |
IHC-P, WB |
| Recommended dilutions: |
IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity: |
Mouse, Rat, Human |
| Crossreactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background: |
EPOR dimerizes triggering the JAK2/STAT5 signaling cascade, In some cell types, Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling, May also activate the LYN tyrosine kinase, Mediates erythropoietin-induced erythroblast proliferation and differentiation, Upon EPO stimulation, can also activate STAT1 and STAT3, Receptor for erythropoietin |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
EPOR Conjugated |
| Short name: |
Conjugated, EPOR Antibody |
| Technique: |
antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label: |
Biotin |
| Alternative name: |
biotinilated coupled, erythropoietin receptor (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
EPO-R, EPOR and IDBG-29281 and ENSG00000187266 and 2057, EPOR and IDBG-643528 and ENSBTAG00000008197 and 281144, Epor and IDBG-142378 and ENSMUSG00000006235 and 13857, Extracellular, identical protein binding, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0004900 and erythropoietin receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007165 and signal transduction and biological process this GO :0007420 and brain development and biological process this GO :0007507 and heart development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0038162 and erythropoietin-mediated signaling pathway and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0046697 and decidualization and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0004900 : erythropoietin receptor activity and also this GO :0005515 : protein binding and also this GO :0042802 : identical protein binding, this GO :0004900 : erythropoietin receptor activity, this GO :0005515 : protein binding, this GO :0042802 : identical protein binding, erythropoietin receptor |
| Identity: |
3416 |
| Gene: |
EPOR |
More about : EPOR |
| Long gene name: |
erythropoietin receptor |
| Locus: |
19p13, 2 |
| Discovery year: |
1990-05-14 |
| GenBank acession: |
M34986 |
| Entrez gene record: |
2057 |
| Classification: |
Fibronectin type III domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000182027 |