| Long name: |
UPK3A Primary Polyclonal Antibody |
| Also known as: |
UPK3A PAb |
| Category: |
Primary Antibodies |
| Conjugation: |
Unconjugated |
| Target Antigen: |
UPK3A |
| Specificity: |
This is a highly specific antibody against UPK3A |
| Modification(s): |
None |
| Modification site(s): |
Unmodified antibody |
| Clonality: |
Polyclonal antibody |
| Clone number: |
Polyclonal antibody |
| Concentration: |
1ug per 1ul |
| Source: |
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human UPK3A |
| Tested Applications: |
IF(IHC-P), IHC-P, WB |
| Recommended dilutions: |
IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity: |
Mouse, Rat, Human |
| Cross reactive species details: |
not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen: |
Family members are conserved among several species, The uroplakin family comprises UPIa, These plaques are thought to strengthen the urothelium and reduce the risk of rupturing during ladder distention, They are also expressed in a majority of transitional cell carcinomas of the bladder (TCCs), They are composed of four major integral membrane proteins called uroplakins (UP), This pairing is required for normal urothelial plaque formation and is regulated by proteolytic processing of the uroplakin proteins, UPII, UPIa and UPIb form tightly packed structures with UPII and UPIII, UPIb, Uroplakins are expressed in normal urothelium and are used as specific markers of urothelial differentiation, and UPIII, dog, including human, mouse, pig and sheep, rabbit, rat, respectively, which cover the apical surface of the urothelium, which make the uroplakins a useful marker for detecting bladder cancer metastasis and for staging and monitoring chemotherapeutic response, The asymmetric unit membrane (AUM) forms numerous plaques |
| Purification method: |
This antibody was purified via Protein A |
| Storage conditions: |
50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names: |
MGC119178, OTTHUMP00000028951, UP III, UP3A, UPIII, UPIIIA, UPK 3, UPK 3A, UPK3, UPK3A, UPK3A_HUMAN, Uroplakin 3A, Uroplakin III, Uroplakin-3a, Uroplakin3A, UroplakinIII, Uroplakin III |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target: |
UPK3A |
| Short name: |
UPK3A Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
UPK3A (Antibody to) |
| Alternative technique: |
antibodies |
| Identity: |
12580 |
| Gene: |
UPK3A |
More about : UPK3A |
| Long gene name: |
uroplakin 3A |
| Synonyms gene: |
UPK3 |
| Synonyms gene name: |
uroplakin 3 |
| Locus: |
22q13, 31 |
| Discovery year: |
1992-07-31 |
| GenBank acession: |
AB010637 |
| Entrez gene record: |
7380 |
| Pubmed identfication: |
9818021 |
| RefSeq identity: |
NM_006953 |
| Havana BLAST/BLAT: |
OTTHUMG00000151339 |