| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
Neurexin 1 beta |
| Specificity: |
Neurexin 1 beta, This antibody will detect Neurexin 1 and Neurexin 1 beta |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Extracellular |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human Neurexin 1 beta |
| Gene ID: |
9378 |
| Swiss Prot: |
Q9ULB1 |
| Applications: |
IF(IHC-P), FCM |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission, Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions, Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity), Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2, Function is isoform-specific, In vitro, Likewise, May be involved in specification of excitatory synapses, They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery, They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland, a subtype of glutamate-gated ion channels, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, exocytosis of secretory granules and regulation of signal transmission, triggers the de novo formation of presynaptic structures, Cell surface protein involved in cell-cell-interactions |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
Hs, KIAA0578, NRXN1, Neurexin I-alpha, Neurexin-1, Neurexin-1-alpha, SCZD17, 22998, PTHSL2 |
| Also known as: |
Neurexin 1 beta Polyclonal Antibody |
| Other name: |
Anti-Neurexin 1 beta Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
Neurexin 1 beta |
| Short name: |
Anti-Neurexin 1 beta (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Neurexin 1 b (polyclonal) |
| Alternative technique: |
polyclonals |