| Also known as: |
PLP1 / Myelin PLP |
| Other names: |
Lipophilin, Myelin proteolipid protein, lipophilin, major myelin proteolipid protein, myelin proteolipid protein, proteolipid protein 1, myelin proteolipid protein isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
PLP1 |
| Other gene names: |
GPM6C, HLD1, MMPL, PLP, PLP, PLP, PLP/DM20, PLP1, PMD, SPG2, PLP1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG2a |
| Clone: |
plpc1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Mammal, the reactivity of the antibody may extend to other species which are not listed hereby, Bovine |
| Specificity and cross-reactivity: |
PLP encodes the major protein components of compact CNS myelin and mutations in the PLP gene can lead to severe dysmyelinating disease, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This Recognizes DM20, This particular antibody might cross react with speacies outside of the listed ones, Recognizes myelin proteolipid protein (PLP) in many mammalian species |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
0, Sourced in TCS, 09% sodium azide, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freeze/thaw may reduce the activity, For longer periods of time, Store the antibodies in an undiluted form, freeze the antibody and keep it at -20 degrees Celsius, Keep the antibody refrigerated at +4 degrees Celsius for short periods of time |
| Tested applications:: |
IHC - Frozen), Western Blot (WB), Immunohistochemistry (IHC - Paraffin |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24° |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ plpc1] (IgG2a) PLP1 / Myelin PLP |
| Short name: |
Mouse Monoclonal [clone plpc1] (IgG2a) PLP1 / Myelin PLP Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG2a |
| Species: |
Bos Taurus genes are available form the Bovine Genome database, Mouses, Bovine |
| Alternative name: |
Mouse monoclonal [clonality plpc1] (IgG2a) to Bovine proteolipid protein 1 / Myelin PLP (Antibody to) |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
GPM6C and HLD1 and MMPL and PLP and PLP/DM20 and PMD and SPG2, PLP1 and IDBG-633948 and ENSBTAG00000006977 and 281410, PLP1 and IDBG-80835 and ENSG00000123560 and 5354, Plasma membranes, Plp1 and IDBG-173392 and ENSMUSG00000031425 and 18823, structural constituent of myelin sheath, this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007229 and integrin-mediated signaling pathway and biological process this GO :0007268 and synaptic transmission and biological process this GO :0008219 and cell death and biological process this GO :0008366 and axon ensheathment and biological process this GO :0010001 and glial cell differentiation and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0014002 and astrocyte development and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0019911 and structural constituent of myelin sheath and molecular function this GO :0021762 and substantia nigra development and biological process this GO :0022010 and central nervous system myelination and biological process this GO :0042552 and myelination and biological process this GO :0042759 and long-chain fatty acid biosynthetic process and biological process this GO :0043209 and myelin sheath and cellular component this GO :0048469 and cell maturation and biological process this GO :0061564 and axon development and biological process, this GO :0005198 : structural molecule activity, this GO :0005198 : structural molecule activity and also this GO :0005515 : protein binding and also this GO :0019911 : structural constituent of myelin sheath, this GO :0005515 : protein binding, this GO :0019911 : structural constituent of myelin sheath, proteolipid protein 1 |
| Identity: |
9086 |
| Gene: |
PLP1 |
More about : PLP1 |
| Long gene name: |
proteolipid protein 1 |
| Synonyms gene: |
SPG2 PLP |
| Synonyms gene name: |
spastic paraplegia 2, uncomplicated |
| Synonyms: |
GPM6C |
| Synonyms name: |
Pelizaeus-Merzbacher disease |
| Locus: |
Xq22, 2 |
| Discovery year: |
2001-06-22 |
| GenBank acession: |
M27110 |
| Entrez gene record: |
5354 |
| Havana BLAST/BLAT: |
OTTHUMG00000022111 |
| Locus Specific Databases: |
Mental Retardation database |