| Also known as: |
SELP / P-Selectin / CD62P |
| Other names: |
CD62 antigen-like family member P, CD62 antigen-like family member P, CD_antigen: CD62P, GMP-140, GMP-140, Granule membrane protein 140, LECAM3, Leukocyte-endothelial cell adhesion molecule 3, P-selectin, P-selectin, PADGEM, Platelet activation dependent granule-external membrane protein, antigen CD62), granule membrane protein 140, granulocyte membrane protein, leukocyte-endothelial cell adhesion molecule 3, platelet activation dependent granule-external membrane protein, platelet alpha-granule membrane protein, selectin P (granule membrane protein 140kDa, P-selectin |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
SELP |
| Other gene names: |
CD62, CD62P, GMP-140, GMP140, GMRP, GRMP, GRMP, LECAM3, LECAM3, PADGEM, PADGEM, PSEL, SELP, SELP |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
2, 5, KO, Psel |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Pig, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
CD62P is expressed by activated platelets and endothelial cells, P-selectin-deficient mice were immunized with a pre-B-cell line transfected with human P-selectin cDNA, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, To produce this mAb, a 140kD glycoprotein also known as P-selectin, and plays an important role in adhesive processes between leucocytes and endothelial cells, Recognizes the CD62P cell surface antigen |
| Purification method: |
Affinity Purified |
| Form/Appearance: |
0, Sourced in TCS, pH 7, 09% sodium azide, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity, For longer storage the antibody should be kept at -20 degrees Celsius, For short term storage keep the antibody at +4 degrees Celsius |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
2, 5] (IgG1) SELP / P-Selectin / CD62P, KO, Monoclonal [ Psel |
| Short name: |
2, 5] (IgG1) SELP / P-Selectin / CD62P Antibody, KO, Mouse Monoclonal [clone Psel |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
antigen CD62) / P-Selectin / CD62P (Antibody to), sapiens selectin P (granule membrane protein 140kDa, 2, 5] (IgG1) to H, KO, Mouse monoclonal [clonality Psel |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
CD62 and CD62P and GMP140 and GRMP and LECAM3 and PADGEM and PSEL, SELP and IDBG-104675 and ENSG00000174175 and 6403, SELP and IDBG-631778 and ENSBTAG00000020755 and 281486, Selp and IDBG-202346 and ENSMUSG00000026580 and 20344, antigen CD62), nuclei, oli this GO saccharide binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0001948 and glycoprotein binding and molecular function this GO :0002576 and platelet degranulation and biological process this GO :0002687 and positive regulation of leukocyte migration and biological process this GO :0005515 and protein binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007155 and cell adhesion and biological process this GO :0007157 and heterophilic cell-cell adhesion and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007596 and blood coagulation and biological process this GO :0008201 and heparin binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0010572 and positive regulation of platelet activation and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0030168 and platelet activation and biological process this GO :0030246 and carbohydrate binding and molecular function this GO :0031088 and platelet dense granule membrane and cellular component this GO :0031092 and platelet alpha granule membrane and cellular component this GO :0032496 and response to lipopolysaccharide and biological process this GO :0033623 and regulation of integrin activation and biological process this GO :0033691 and sialic acid binding and molecular function this GO :0042806 and fucose binding and molecular function this GO :0043208 and glycosphin this GO lipid binding and molecular function this GO :0048306 and calcium-dependent protein binding and molecular function this GO :0050829 and defense response to Gram-negative bacterium and biological process this GO :0050900 and leukocyte migration and biological process this GO :0050901 and leukocyte tethering or rolling and biological process this GO :0070492 and oli this GO saccharide binding and molecular function, this GO :0001530 : lipopolysaccharide binding, this GO :0001530 : lipopolysaccharide binding and also this GO :0001948 : glycoprotein binding and also this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0030246 : carbohydrate binding and also this GO :0033691 : sialic acid binding and also this GO :0042806 : fucose binding and also this GO :0043208 : glycosphin this GO lipid binding and also this GO :0048306 : calcium-dependent protein binding and also this GO :0070492 : oli this GO saccharide binding, this GO :0001948 : glycoprotein binding, this GO :0005515 : protein binding, this GO :0008201 : heparin binding, this GO :0030246 : carbohydrate binding, this GO :0033691 : sialic acid binding, this GO :0042806 : fucose binding, this GO :0043208 : glycosphin this GO lipid binding, this GO :0048306 : calcium-dependent protein binding, this GO :0070492 : oli this GO saccharide binding, selectin P (granule membrane protein 140kDa |
| Identity: |
10721 |
| Gene: |
SELP |
More about : SELP |
| Long gene name: |
selectin P |
| Synonyms gene: |
GRMP |
| Synonyms gene name: |
antigen CD62) , antigen CD62) selectin P (granule membrane protein 140kDa, selectin P (granule membrane protein 140kD |
| Synonyms: |
CD62 PSEL PADGEM GMP140 CD62P |
| Synonyms name: |
antigen CD62 granule membrane protein 140kDa |
| Locus: |
1q24, 2 |
| Discovery year: |
1989-06-30 |
| GenBank acession: |
BC068533 |
| Entrez gene record: |
6403 |
| Pubmed identfication: |
1375831 |
| RefSeq identity: |
NM_003005 |
| Classification: |
Sushi domain containing Selectins CD molecules C-type lectin domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000034685 |