| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
WNT4 |
| Specificity: |
This antibody reacts specifically with WNT4 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Secreted |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human WNT4 |
| Gene ID: |
54361 |
| Swiss Prot: |
P56705 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Is likely to signal over only few cell diameters (By similarity), May be a signaling molecule which affects the development of discrete regions of tissues, Overexpression may be associated with abnormal proliferation in human breast tissue, Probable developmental protein, Ligand for members of the frizzled family of seven transmembrane receptors |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
WNT-4 |
| Also known as: |
WNT4 Polyclonal Antibody |
| Other name: |
Anti-WNT4 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
WNT4 |
| Short name: |
Anti-WNT4 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, member 4 (polyclonal), antibody to-wingless-classification MMTV integration site family |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0048018 and receptor a this GO nist activity and molecular function this GO :0048599 and oocyte development and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048856 and anatomical structure development and biological process this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0051894 and positive regulation of focal adhesion assembly and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060126 and somatotropin secreting cell differentiation and biological process this GO :0060129 and thyroid-stimulating hormone-secreting cell differentiation and biological process this GO :0060231 and mesenchymal to epithelial transition and biological process this GO :0060748 and tertiary branching involved in mammary gland duct morphogenesis and biological process this GO :0060993 and kidney morphogenesis and biological process this GO :0061045 and negative regulation of wound healing and biological process this GO :0061180 and mammary gland epithelium development and biological process this GO :0061184 and positive regulation of dermatome development and biological process this GO :0061205 and paramesonephric duct development and biological process this GO :0061369 and negative regulation of testicular blood vessel morphogenesis and biological process this GO :0071560 and cellular response to transforming growth factor beta stimulus and biological process this GO :0072033 and renal vesicle formation and biological process this GO :0072034 and renal vesicle induction and biological process this GO :0072162 and metanephric mesenchymal cell differentiation and biological process this GO :0072164 and mesonephric tubule development and biological process this GO :0072174 and metanephric tubule formation and biological process this GO :0072210 and metanephric nephron development and biological process this GO :0072273 and metanephric nephron morphogenesis and biological process this GO :0090002 and establishment of protein localization to plasma membrane and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :0090263 and positive regulation of canonical Wnt signaling pathway and biological process this GO :2000019 and negative regulation of male this GO nad development and biological process this GO :2000066 and positive regulation of cortisol biosynthetic process and biological process this GO :2000225 and negative regulation of testosterone biosynthetic process and biological process this GO :2001234 and negative regulation of apoptotic signaling pathway and biological process, Extracellular, WNT4 and IDBG-645527 and ENSBTAG00000022671 and 789600, WNT4 and IDBG-93664 and ENSG00000162552 and 54361, Wnt4 and IDBG-198435 and ENSMUSG00000036856 and 22417, member 4, receptor a this GO nist activity, this GO :0001656 and metanephros development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001822 and kidney development and biological process this GO :0001823 and mesonephros development and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001838 and embryonic epithelial tube formation and biological process this GO :0001889 and liver development and biological process this GO :0003714 and transcription corepressor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005109 and frizzled binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005788 and endoplasmic reticulum lumen and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006702 and androgen biosynthetic process and biological process this GO :0007275 and multicellular organismal development and biological process this GO :0007276 and gamete generation and biological process this GO :0007548 and sex differentiation and biological process this GO :0008584 and male this GO nad development and biological process this GO :0008585 and female this GO nad development and biological process this GO :0009267 and cellular response to starvation and biological process this GO :0009986 and cell surface and cellular component this GO :0010629 and negative regulation of gene expression and biological process this GO :0010894 and negative regulation of steroid biosynthetic process and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0018345 and protein palmitoylation and biological process this GO :0022407 and regulation of cell-cell adhesion and biological process this GO :0030154 and cell differentiation and biological process this GO :0030182 and neuron differentiation and biological process this GO :0030237 and female sex determination and biological process this GO :0030325 and adrenal gland development and biological process this GO :0030336 and negative regulation of cell migration and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0031012 and extracellular matrix and cellular component this GO :0032321 and positive regulation of Rho GTPase activity and biological process this GO :0032349 and positive regulation of aldosterone biosynthetic process and biological process this GO :0032967 and positive regulation of collagen biosynthetic process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033080 and immature T cell proliferation in thymus and biological process this GO :0035239 and tube morphogenesis and biological process this GO :0035567 and non-canonical Wnt signaling pathway and biological process this GO :0038030 and non-canonical Wnt receptor signaling pathway via MAPK cascade and biological process this GO :0040037 and negative regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0042445 and hormone metabolic process and biological process this GO :0045165 and cell fate commitment and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045836 and positive regulation of meiosis and biological process this GO :0045892 and negative regulation of transcription, this GO :0003714 : transcription corepressor activity, this GO :0003714 : transcription corepressor activity and also this GO :0005102 : receptor binding and also this GO :0005109 : frizzled binding and also this GO :0005515 : protein binding and also this GO :0048018 : receptor a this GO nist activity, this GO :0005102 : receptor binding, this GO :0005109 : frizzled binding, this GO :0005515 : protein binding, this GO :0048018 : receptor a this GO nist activity, wingless-type MMTV integration site family |
| Identity: |
12783 |
| Gene: |
WNT4 |
More about : WNT4 |
| Long gene name: |
Wnt family member 4 |
| Synonyms gene name: |
member 4 , wingless-type MMTV integration site family |
| Locus: |
1p36, 12 |
| Discovery year: |
2000-07-31 |
| GenBank acession: |
AL031281 |
| Entrez gene record: |
54361 |
| Pubmed identfication: |
8168088 |
| Classification: |
Wnt family Endogenous ligands |
| Havana BLAST/BLAT: |
OTTHUMG00000002894 |