| Also known as: |
CD81 |
| Other names: |
26 kDa cell surface protein TAPA-1, 26 kDa cell surface protein TAPA-1, CD81 antigen, CD81 antigen, CD81 antigen (target of antiproliferative antibody 1), CD81 molecule, Target of the antiproliferative antibody 1, Tetraspanin-28, tetraspanin-28, tspan-28, CD81 antigen |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD81 |
| Other gene names: |
CD81, CVID6, S5, TAPA1, TAPA1, TSPAN28, TSPAN28, Tspan-28, 7, CD81 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
Hamster IgG |
| Clone: |
EAT 2 |
| Host organism: |
Hamster |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Mouse (Mus musculus) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, CD81 (TAPA-1) (Mouse CD81 (TAPA-1)) |
| Form/Appearance: |
0, ), 02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/ml, Biotin (Biotin conjugated Ig buffered in PBS |
| Concentration: |
1 miligram per 1 mililiter, Antibody Concentration: 0 |
| Storage and shipping: |
Avoid freeze/thaw cycles, For long term storage, aliquot and freeze unused portion the antibody should be stored at -20 degrees Celsius, in volumes appropriate for single usage, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC) |
| Properties: |
Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, Biotin conjugates can be detected by horseradish peroxidase |
| Conjugation: |
Biotinylated |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| About: |
Rats , There are less rat- than mouse clones however, Rats are used to make rat monoclonal anti mouse antibodies, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Gene target: |
Eat2) IgG1), / CD81 |
| Short name: |
(Clone Eat2) (mouse IgG1), Anti-Mouse/ CD81 |
| Technique: |
mouses, Mouse |
| Host: |
Rat |
| Isotype: |
IgG1 |
| Label: |
Biotin |
| Species: |
Mouses, Rats, Rat |
| Alternative name: |
biotinilated (clonality Eat2) (mouse IgG1), antibody to-Mouse/Rat CD81 molecule |
| Alternative technique: |
murine |
| Alternative to gene target: |
CD81 and IDBG-22455 and ENSG00000110651 and 975, CD81 and IDBG-645214 and ENSBTAG00000047495 and 511435, CVID6 and S5, Cd81 and IDBG-212677 and ENSMUSG00000037706 and 12520, Cell surfaces, MHC class II protein complex binding, this GO :0000187 and activation of MAPK activity and biological process this GO :0001772 and immunological synapse and cellular component this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006661 and phosphatidylinositol biosynthetic process and biological process this GO :0008104 and protein localization and biological process this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0023026 and MHC class II protein complex binding and molecular function this GO :0031982 and vesicle and cellular component this GO :0043128 and positive regulation of 1-phosphatidylinositol 4-kinase activity and biological process this GO :0046488 and phosphatidylinositol metabolic process and biological process this GO :0046718 and viral entry into host cell and biological process this GO :0046813 and receptor-mediated virion attachment to host cell and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050776 and regulation of immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0005515 : protein binding, this GO :0005515 : protein binding and also this GO :0023026 : MHC class II protein complex binding, this GO :0023026 : MHC class II protein complex binding, 7 and TAPA1 and TSPAN28, CD81 molecule |
| Identity: |
1701 |
| Gene: |
CD81 |
More about : CD81 |
| Long gene name: |
CD81 molecule |
| Synonyms gene: |
TAPA1 |
| Synonyms gene name: |
CD81 antigen (target of antiproliferative antibody 1) |
| Synonyms: |
TAPA-1 TSPAN28 |
| Locus: |
11p15, 5 |
| Discovery year: |
1992-10-21 |
| Entrez gene record: |
975 |
| Pubmed identfication: |
1650385 |
| RefSeq identity: |
NM_004356 |
| Classification: |
CD molecules Tetraspanins |
| Havana BLAST/BLAT: |
OTTHUMG00000009892 |
| Locus Specific Databases: |
LRG_142 |