| known also as: |
Anti-RABBIT ANTI HUMAN MDC |
| known also as: |
RABBIT ANTI HUMAN MDC |
| known also as: |
Lapin ANTI Homo sapiens MDC |
| known also as: |
MDC |
| Other names: |
C-C motif chemokine 22, C-C motif chemokine 22, CC chemokine STCP-1, CC chemokine STCP-1, MDC(1-69), MDC(1-69), Macrophage-derived chemokine, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1, chemokine (C-C motif) ligand 22, macrophage-derived chemokine, member 22, small inducible cytokine A22, small inducible cytokine subfamily A (Cys-Cys), small-inducible cytokine A22, stimulated T cell chemotactic protein 1, stimulated T-cell chemotactic protein 1, C-C motif chemokine 22 |
| Gene name: |
MDC |
| Other gene names: |
A-152E5, ABCD-1, CCL22, DC/B-CK, MDC, MDC, SCYA22, SCYA22, STCP-1, 1, CCL22 |
| Category: |
Antibodies |
| Clonality: |
Polyclonal |
| Immunoglobulin isotype: |
Polyclonal IgG |
| Clone: |
Polyclonal antibody |
| Host organism: |
Rabbit |
| Species reactivity: |
Human |
| Specificity and cross-reactivity: |
CCR4 is selectively expressed by Th2 cells and several studies have revealed a link between MDC and another ligand of CCR4, _x000D__x000D_MDC acts as a chemoattractant for monocytes, a member of the CC chemokine family expressed by macrophages, activated T lymphocytes and NK cells, dendritic cells, epithelial cells, fibroblasts and highly expressed in the thymus, known as activation-regulated chemokine (TARC/CCL17), monocyte-derived dendritic cells, otherwise known as CCL22, through binding to chemokine (C-C motif) receptor 4 (CCR4), with Th2-mediated inflammatory disorders such as atopic dermatitis, MDC This item is specific for human MDC (macrophage-derived cytokine) |
| Form/Appearance: |
Purified (Purified IgG - lyophilised) |
| Concentration: |
0mg/ml, IgG concentration 1 |
| Storage and shipping: |
After reconstitution For optimal long term storage, Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 12 months from date of reconstitution, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, productone should be kept at -20 degrees Celsius, productone should be stored undiluted, Prior to reconstitution store at +Store productone at +4 degrees Celsius |
| Tested for:: |
ELISA (EIA), Western Blot (WB), Functional Assay (FA) |
| Description: |
Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target: |
MDC |
| Short name: |
Anti-HUMAN MDC Antibody |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
sapiens MDC (Antibody to), antibody to-H |
| Alternative technique: |
antibodies |
| Identity: |
189 |
| Gene: |
ADAM11 |
More about : ADAM11 |
| Long gene name: |
ADAM metallopeptidase domain 11 |
| Synonyms gene: |
MDC |
| Synonyms gene name: |
a disintegrin and metalloproteinase domain 11 |
| Synonyms name: |
cysteine-rich protein , disintegrin-like, metalloproteinase-like |
| Locus: |
17q21, 31 |
| Discovery year: |
1993-11-01 |
| GenBank acession: |
D17390 |
| Entrez gene record: |
4185 |
| Pubmed identfication: |
8252040 |
| RefSeq identity: |
NM_002390 |
| Classification: |
ADAM metallopeptidase domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000179038 |