| Reacts with: |
Mouse |
| Source: |
proteins, Recombinants or rec |
| Description: |
Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus |
| Molecular Weight: |
26, 5 kD |
| UniProt number: |
P04187 |
| State of the product: |
Liquid |
| Shipping conditions: |
Dry Ice/ice packs |
| Formulation: |
2 um filtered solution of phosphate buffered saline, 4, Supplied as a 0, pH7 |
| Storage recommendations: |
-20°, Please minimize freeze-thaw cycles, stable for 6 months after receipt, C, Store at < |
| Reconstitution: |
Dissolve the lyophilized protein in ddH2O, Do not mix by vortex or pipetting, It is not recommended to reconstitute to a concentration less than 100 &mu, Please aliquot the reconstituted solution to minimize freeze-thaw cycles, Always centrifuge tubes before opening, g/ml |
| Purity: |
and determined by Polyacrylamide gel electrophoresis, Greater than 95% |
| Sequence of the amino acid: |
GEIIGGHEVKPHSRPYMALLSIKDQQPEAICGGFLIREDFVLTAAHCEGSIINVTLGAHNIKEQEKTQQVIPMVKCIPHPDYNPKTFSNDIMLLKLKSKAKRTRAVRPLNLPRRNVNVKPGDVCYVAGWGRMAPMGKYSNTLQEVELTVQKDRECESYFKNRYNKTNQICAGDPKTKRASFRGDSGGPLVCKKVAAGIVSYGYKDGSPPRAFTKVSSFLSWIKKTMKSSVDHHHHHH |
| Levels of endotoxin: |
11 IEU/ug, LAL test shows less than than 0 |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Group: |
recombinants |
| Gene target: |
Granzyme B (G, H) GZMB (C-6His) |
| Short name: |
H) GZMB (C-6His), Recombinant Mouse Granzyme B (G |
| Technique: |
E, coli recombinant proteins are , mouses, novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Species: |
Mouses, Mouse |
| Alternative name: |
cytotoxic T-lymphocyte-associated serine esterase 1) (C-6His), granzyme B (granzyme 2, H), recombinant Mouse Granzyme B (G |
| Alternative technique: |
rec |
| Alternative to gene target: |
BT, CCPI and CGL-1 and CGL1 and CSP-B and CSPB and CTLA1 and CTSGL1 and HLP and SECT, GZMB and IDBG-4054 and ENSG00000100453 and 3002, cytotoxic T-lymphocyte-associated serine esterase 1), nuclei, serine-type peptidase activity, this GO :0001772 and immunological synapse and cellular component this GO :0003824 and catalytic activity and molecular function this GO :0004252 and serine-type endopeptidase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006508 and proteolysis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007219 and Notch signaling pathway and biological process this GO :0008236 and serine-type peptidase activity and molecular function this GO :0008626 and granzyme-mediated apoptotic signaling pathway and biological process this GO :0016020 and membrane and cellular component this GO :0019835 and cytolysis and biological process this GO :0030141 and secretory granule and cellular component this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process, this GO :0003824 : catalytic activity, this GO :0003824 : catalytic activity and also this GO :0004252 : serine-type endopeptidase activity and also this GO :0005515 : protein binding and also this GO :0008236 : serine-type peptidase activity, this GO :0004252 : serine-type endopeptidase activity, this GO :0005515 : protein binding, this GO :0008236 : serine-type peptidase activity, 19365 and IDBG-632083 and ENSBTAG00000010057 and 508646, granzyme B (granzyme 2 |
| Identity: |
4709 |
| Gene: |
GZMB |
More about : GZMB |
| Long gene name: |
granzyme B |
| Synonyms gene: |
CTLA1 CSPB |
| Synonyms gene name: |
cytotoxic T-lymphocyte-associated serine esterase 1) , granzyme B (granzyme 2 |
| Synonyms: |
CCPI CGL-1 CSP-B CGL1 CTSGL1 HLP SECT |
| Synonyms name: |
fragmentin 2 cytotoxic serine protease B cathepsin G-like 1 T-cell serine protease 1-3E granzyme 2 cytotoxic T-lymphocyte-associated serine esterase 1 |
| Locus: |
14q12 |
| Discovery year: |
1989-05-12 |
| GenBank acession: |
BC030195 |
| Entrez gene record: |
3002 |
| Pubmed identfication: |
2323780 |
| RefSeq identity: |
NM_004131 |
| Havana BLAST/BLAT: |
OTTHUMG00000029369 |