| Alternative name 1: |
Clone: 4D12, Mab anti-, TLR5 |
| Alternative name 2: |
Clone: 4D12, Mab antibody-, TLR5 |
| Alternative name 3: |
Clone: 4D12, Mab antibody-, TLR5 |
| Alternative name 4: |
anti-TLR5 Clone: 4D12 |
| Alternative name 5: |
TLR5 Clone: 4D12 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 4D12, TLR5 |
| Short name: |
Mouse Monoclonal antibody- Clone: 4D12, TLR5 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 4D12, toll-like receptor 5 |
| Alternative technique: |
murine |
| Alternative to gene target: |
MELIOS and SLE1 and SLEB1 and TIL3, Plasma membranes, TLR5 and IDBG-106840 and ENSG00000187554 and 7100, TLR5 and IDBG-648348 and ENSBTAG00000000477 and 444870, Tlr5 and IDBG-259066 and ENSMUSG00000079164 and 53791, protein binding, this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005149 and interleukin-1 receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006954 and inflammatory response and biological process this GO :0007165 and signal transduction and biological process this GO :0008584 and male this GO nad development and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0032757 and positive regulation of interleukin-8 production and biological process this GO :0034123 and positive regulation of toll-like receptor signaling pathway and biological process this GO :0034146 and toll-like receptor 5 signaling pathway and biological process this GO :0034166 and toll-like receptor 10 signaling pathway and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0045087 and innate immune response and biological process this GO :0045429 and positive regulation of nitric oxide biosynthetic process and biological process this GO :0050707 and regulation of cytokine secretion and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process, this GO :0004888 : transmembrane signaling receptor activity, this GO :0004888 : transmembrane signaling receptor activity and also this GO :0005149 : interleukin-1 receptor binding and also this GO :0005515 : protein binding, this GO :0005149 : interleukin-1 receptor binding, this GO :0005515 : protein binding, toll-like receptor 5 |
| Identity: |
11851 |
| Gene: |
TLR5 |
More about : TLR5 |
| Long gene name: |
toll like receptor 5 |
| Synonyms gene: |
SLEB1 |
| Synonyms gene name: |
systemic lupus erythematosus susceptibility 1 toll-like receptor 5 |
| Synonyms: |
TIL3 FLJ10052 MGC126430 MGC126431 |
| Synonyms name: |
Toll/interleukin-1 receptor-like protein 3 |
| Locus: |
1q41 |
| Discovery year: |
1998-06-25 |
| Entrez gene record: |
7100 |
| Pubmed identfication: |
9435236 16027372 |
| RefSeq identity: |
NM_003268 |
| Classification: |
Toll like receptors |
| Havana BLAST/BLAT: |
OTTHUMG00000037937 |