| Alternative name 1: |
Clone: 1E4-G5, Mab anti-, NKX2-5 |
| Alternative name 2: |
Clone: 1E4-G5, Mab antibody-, NKX2-5 |
| Alternative name 3: |
Clone: 1E4-G5, Mab antibody-, NKX2-5 |
| Alternative name 4: |
anti-NKX2-5 Clone: 1E4-G5 |
| Alternative name 5: |
NKX2-5 Clone: 1E4-G5 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 1E4-G5, NKX2-5 |
| Short name: |
Mouse Monoclonal antibody- Clone: 1E4-G5, NKX2-5 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal (Antibody to)-, clonality: 1E4-G5, NK2 homeobox 5 |
| Alternative technique: |
murine |
| Alternative to gene target: |
CHNG5 and CSX and CSX1 and HLHS2 and NKX2, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048536 and spleen development and biological process this GO :0048738 and cardiac muscle tissue development and biological process this GO :0051891 and positive regulation of cardioblast differentiation and biological process this GO :0055005 and ventricular cardiac myofibril assembly and biological process this GO :0055007 and cardiac muscle cell differentiation and biological process this GO :0055008 and cardiac muscle tissue morphogenesis and biological process this GO :0055014 and atrial cardiac muscle cell development and biological process this GO :0055015 and ventricular cardiac muscle cell development and biological process this GO :0055117 and regulation of cardiac muscle contraction and biological process this GO :0060037 and pharyngeal system development and biological process this GO :0060038 and cardiac muscle cell proliferation and biological process this GO :0060043 and regulation of cardiac muscle cell proliferation and biological process this GO :0060047 and heart contraction and biological process this GO :0060048 and cardiac muscle contraction and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060261 and positive regulation of transcription initiation from RNA polymerase II promoter and biological process this GO :0060347 and heart trabecula formation and biological process this GO :0060412 and ventricular septum morphogenesis and biological process this GO :0060413 and atrial septum morphogenesis and biological process this GO :0060928 and atrioventricular node cell development and biological process this GO :0060929 and atrioventricular node cell fate commitment and biological process this GO :0060971 and embryonic heart tube left/right pattern formation and biological process this GO :0072358 and cardiovascular system development and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :1901387 and positive regulation of voltage-gated calcium channel activity and biological process, NKX2-5 and IDBG-58041 and ENSG00000183072 and 1482, NKX2-5 and IDBG-628505 and ENSBTAG00000020568 and 538870, Nkx2-5 and IDBG-155464 and ENSMUSG00000015579 and 18091, nuclei, protein heterodimerization activity, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001104 and RNA polymerase II transcription cofactor activity and molecular function this GO :0001190 and RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0001570 and vasculogenesis and biological process this GO :0001947 and heart looping and biological process this GO :0003007 and heart morphogenesis and biological process this GO :0003148 and outflow tract septum morphogenesis and biological process this GO :0003151 and outflow tract morphogenesis and biological process this GO :0003161 and cardiac conduction system development and biological process this GO :0003162 and atrioventricular node development and biological process this GO :0003166 and bundle of His development and biological process this GO :0003168 and Purkinje myocyte differentiation and biological process this GO :0003208 and cardiac ventricle morphogenesis and biological process this GO :0003211 and cardiac ventricle formation and biological process this GO :0003221 and right ventricular cardiac muscle tissue morphogenesis and biological process this GO :0003222 and ventricular trabecula myocardium morphogenesis and biological process this GO :0003278 and apoptotic process involved in heart morphogenesis and biological process this GO :0003285 and septum secundum development and biological process this GO :0003342 and proepicardium development and biological process this GO :0003350 and pulmonary myocardium development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007507 and heart development and biological process this GO :0007512 and adult heart development and biological process this GO :0008134 and transcription factor binding and molecular function this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010667 and negative regulation of cardiac muscle cell apoptotic process and biological process this GO :0010735 and positive regulation of transcription via serum response element binding and biological process this GO :0010736 and serum response element binding and molecular function this GO :0010765 and positive regulation of sodium ion transport and biological process this GO :0010832 and negative regulation of myotube differentiation and biological process this GO :0030097 and hemopoiesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0030509 and BMP signaling pathway and biological process this GO :0030878 and thyroid gland development and biological process this GO :0035050 and embryonic heart tube development and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045214 and sarcomere organization and biological process this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045823 and positive regulation of heart contraction and biological process this GO :0045892 and negative regulation of transcription, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978 : RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0001104 : RNA polymerase II transcription cofactor activity and also this GO :0001190 : RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0005515 : protein binding and also this GO :0008134 : transcription factor binding and also this GO :0010736 : serum response element binding and also this GO :0042803 : protein homodimerization activity and also this GO :0043565 : sequence-specific DNA binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0046982 : protein heterodimerization activity, this GO :0001077 : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0001104 : RNA polymerase II transcription cofactor activity, this GO :0001190 : RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003705 : RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0005515 : protein binding, this GO :0008134 : transcription factor binding, this GO :0010736 : serum response element binding, this GO :0042803 : protein homodimerization activity, this GO :0043565 : sequence-specific DNA binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0046982 : protein heterodimerization activity, 5 and NKX2E and NKX4-1 and VSD3, NK2 homeobox 5 |
| Identity: |
2488 |
| Gene: |
NKX2-5 |
More about : NKX2-5 |
| Long gene name: |
NK2 homeobox 5 |
| Synonyms gene: |
CSX NKX2E |
| Synonyms gene name: |
cardiac-specific homeo box NK2 transcription factor related, locus 5 (Drosophila) |
| Synonyms: |
CSX1 NKX2, 5 NKX4-1 |
| Synonyms name: |
tinman paralog (Drosophila) |
| Locus: |
5q34 |
| Discovery year: |
1995-02-07 |
| GenBank acession: |
AB021133 |
| Pubmed identfication: |
7665173 8900537 |
| Classification: |
NKL subclass homeoboxes and pseudogenes |
| Havana BLAST/BLAT: |
OTTHUMG00000130522 |
| Locus Specific Databases: |
LRG_671 |