| Alternative name 1: |
Alexa Fluor 488 conj, Clone: 5A1-1422, Rat Mab anti-Mouse, flow, ABCA1 |
| Alternative name 2: |
Alexa Fluor 488 conj, Clone: 5A1-1422, Rat Mab antibody-Mouse, flow, ABCA1 |
| Alternative name 3: |
Alexa Fluor 488 conj, Clone: 5A1-1422, Rattus norvegicus Mab antibody-Mus musculus, flow, ABCA1 |
| Alternative name 4: |
anti-ABCA1 Clone: 5A1-1422 flow Alexa Fluor 488 |
| Alternative name 5: |
ABCA1 Clone: 5A1-1422 flow Alexa Fluor 488 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Rats are used to make rat monoclonal anti mouse antibodies, Rats , There are less rat- than mouse clones however, Monoclonals of this antigen are available in different clones, Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats, genes from rodents , of the genus |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Rattus norvegicus, Mus musculus |
| French translation: |
anticorps |
| Gene target: |
Monoclonal 5A1-1422, conj, ABCA1 |
| Short name: |
Alexa Fluor 488 conj, Clone: 5A1-1422, Mouse Monoclonal antibody-Mouse, ABCA1 |
| Technique: |
Monoclonals or monoclonal antibodies, mouses, Mouse |
| Host: |
Rat |
| Species: |
Mouses, Rats, Mouse |
| Alternative name: |
Alexa Fluor 488 conj, Rat Mouse monoclonal (Antibody to)-Mouse, clonality: 5A1-1422, flow, member 1, sub-family A (ABC1), adenosine triphosphate-binding cassette |
| Alternative technique: |
murine |
| Alternative to gene target: |
ABC-1 and ABC1 and CERP and HDLDT1 and TGD, ABCA1 and IDBG-79441 and ENSG00000165029 and 19, ATPase binding, Abca1 and IDBG-147642 and ENSMUSG00000015243 and 11303, BT, Cell surfaces, engulfment and biological process this GO :0007040 and lysosome organization and biological process this GO :0007186 and G-protein coupled receptor signaling pathway and biological process this GO :0007584 and response to nutrient and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0008509 and anion transmembrane transporter activity and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010745 and negative regulation of macrophage derived foam cell differentiation and biological process this GO :0010875 and positive regulation of cholesterol efflux and biological process this GO :0010887 and negative regulation of cholesterol storage and biological process this GO :0015485 and cholesterol binding and molecular function this GO :0015914 and phospholipid transport and biological process this GO :0016197 and endosomal transport and biological process this GO :0016887 and ATPase activity and molecular function this GO :0017127 and cholesterol transporter activity and molecular function this GO :0019905 and syntaxin binding and molecular function this GO :0030139 and endocytic vesicle and cellular component this GO :0030301 and cholesterol transport and biological process this GO :0030819 and positive regulation of cAMP biosynthetic process and biological process this GO :0031267 and small GTPase binding and molecular function this GO :0032367 and intracellular cholesterol transport and biological process this GO :0032489 and regulation of Cdc42 protein signal transduction and biological process this GO :0033344 and cholesterol efflux and biological process this GO :0033700 and phospholipid efflux and biological process this GO :0034185 and apolipoprotein binding and molecular function this GO :0034186 and apolipoprotein A-I binding and molecular function this GO :0034188 and apolipoprotein A-I receptor activity and molecular function this GO :0034364 and high-density lipoprotein particle and cellular component this GO :0034380 and high-density lipoprotein particle assembly and biological process this GO :0034616 and response to laminar fluid shear stress and biological process this GO :0038027 and apolipoprotein A-I-mediated signaling pathway and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042158 and lipoprotein biosynthetic process and biological process this GO :0042493 and response to drug and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043231 and intracellular membrane-bounded organelle and cellular component this GO :0043691 and reverse cholesterol transport and biological process this GO :0044255 and cellular lipid metabolic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045332 and phospholipid translocation and biological process this GO :0045335 and pha this GO cytic vesicle and cellular component this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050702 and interleukin-1 beta secretion and biological process this GO :0051117 and ATPase binding and molecular function this GO :0055091 and phospholipid homeostasis and biological process this GO :0055098 and response to low-density lipoprotein particle stimulus and biological process this GO :0060155 and platelet dense granule organization and biological process this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071300 and cellular response to retinoic acid and biological process this GO :0071397 and cellular response to cholesterol and biological process, member 1, sub-family A (ABC1), this GO :0002790 and peptide secretion and biological process this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005543 and phospholipid binding and molecular function this GO :0005548 and phospholipid transporter activity and molecular function this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006200 and ATP catabolic process and biological process this GO :0006497 and protein lipidation and biological process this GO :0006911 and pha this GO cytosis, this GO :0005102 : receptor binding, this GO :0005102 : receptor binding and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0005543 : phospholipid binding and also this GO :0005548 : phospholipid transporter activity and also this GO :0008509 : anion transmembrane transporter activity and also this GO :0015485 : cholesterol binding and also this GO :0016887 : ATPase activity and also this GO :0017127 : cholesterol transporter activity and also this GO :0019905 : syntaxin binding and also this GO :0031267 : small GTPase binding and also this GO :0034185 : apolipoprotein binding and also this GO :0034186 : apolipoprotein A-I binding and also this GO :0034188 : apolipoprotein A-I receptor activity and also this GO :0051117 : ATPase binding, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0005543 : phospholipid binding, this GO :0005548 : phospholipid transporter activity, this GO :0008509 : anion transmembrane transporter activity, this GO :0015485 : cholesterol binding, this GO :0016887 : ATPase activity, this GO :0017127 : cholesterol transporter activity, this GO :0019905 : syntaxin binding, this GO :0031267 : small GTPase binding, this GO :0034185 : apolipoprotein binding, this GO :0034186 : apolipoprotein A-I binding, this GO :0034188 : apolipoprotein A-I receptor activity, this GO :0051117 : ATPase binding, 89249 and IDBG-637291 and ENSBTAG00000020661 and 535379, ATP-binding cassette |
| Identity: |
29 |
| Gene: |
ABCA1 |
More about : ABCA1 |
| Long gene name: |
ATP binding cassette subfamily A member 1 |
| Synonyms gene: |
ABC1 HDLDT1 |
| Synonyms gene name: |
ATP-binding cassette, member 1 , sub-family A (ABC1) |
| Synonyms: |
TGD |
| Synonyms name: |
Tangier disease |
| Locus: |
9q31, 1 |
| Discovery year: |
2005-03-17 |
| GenBank acession: |
AJ012376 |
| Entrez gene record: |
19 |
| Pubmed identfication: |
8088782 10431236 10431237 10431238 |
| RefSeq identity: |
NM_005502 |
| Classification: |
ATP binding cassette subfamily A |
| Havana BLAST/BLAT: |
OTTHUMG00000020417 |