| Alternative name 1: |
18-20kD PI-linked, Clone: MEM-43, FITC conj, Leukocyte, Mab anti-Human, Red Blood Cell, CD59 |
| Alternative name 2: |
18-20kD PI-linked, Clone: MEM-43, FITC conj, Leukocyte, Mab antibody-Human, Red Blood Cell, CD59 |
| Alternative name 3: |
18-20kD PI-linked, Clone: MEM-43, FITC conj, Leukocyte, Mab antibody-Homo sapiens, Red Blood Cell, CD59 |
| Alternative name 4: |
anti-CD59 Red Blood Cell Leukocyte 18-20kD PI-linked Clone: MEM-43 |
| Alternative name 5: |
CD59 Red Blood Cell Leukocyte 18-20kD PI-linked Clone: MEM-43 |
| Clonality: |
Monoclonal Antibody |
| Description: |
Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling: |
Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory: |
For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, Human proteins, Mainly analyzed are human serum, Modern , When excited at 488 nanometers, accurate-monoclonals FITC is highly sensitive to pH extremes, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, plasma, primarily , saliva, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, urine, , (Homo sapiens, Homo sapiens sapiens), This accurate-monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, humans , ssp |
| Conjugation: |
red dye, Anti-FITC Antibody |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
18-20kD PI-linked, MEM-43, Monoclonal conj, Red Leukocyte, CD59 |
| Short name: |
18-20kD PI-linked, Clone: MEM-43, Leukocyte, Mouse Monoclonal antibody- FITC conj, Red Blood Cell, CD59 |
| Technique: |
Fluorescein, Monoclonals or monoclonal antibodies, mouses, Mouse |
| Label: |
Red |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
18-20kD PI-linked, Leukocyte, Mouse monoclonal (Antibody to)-H, Red Blood cellular, clonality: MEM-43, complement regulatory protein, fluorecein conj, sapiens, CD59 molecule |
| Alternative technique: |
murine |
| Alternative to gene target: |
16, CD59 and IDBG-38813 and ENSG00000085063 and 966, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574, Extracellular, complement regulatory protein, protein binding, this GO :0001775 and cell activation and biological process this GO :0001848 and complement binding and molecular function this GO :0001971 and negative regulation of activation of membrane attack complex and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009986 and cell surface and cellular component this GO :0016020 and membrane and cellular component this GO :0030449 and regulation of complement activation and biological process this GO :0031362 and anchored component of external side of plasma membrane and cellular component this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042383 and sarcolemma and cellular component this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043218 and compact myelin and cellular component this GO :0045087 and innate immune response and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, this GO :0001848 : complement binding, this GO :0001848 : complement binding and also this GO :0005515 : protein binding, this GO :0005515 : protein binding, 3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 molecule |
| Identity: |
1689 |
| Gene: |
CD59 |
More about : CD59 |
| Long gene name: |
CD59 molecule |
| Synonyms gene: |
MIC11 MIN1 MSK21 MIN2 MIN3 |
| Synonyms gene name: |
CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16, EJ16, EJ30, EL32 and G344) CD59 antigen, complement regulatory protein , complement regulatory protein CD59 molecule, 3A5 |
| Synonyms: |
16, 3A5 EJ16 EJ30 EL32 G344 p18-20 |
| Locus: |
11p13 |
| Discovery year: |
1989-06-30 |
| Entrez gene record: |
966 |
| Pubmed identfication: |
7691713 |
| RefSeq identity: |
NM_203329 |
| Classification: |
Complement system CD molecules LY6/PLAUR domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000166270 |
| Locus Specific Databases: |
CD59base: Mutation registry for CD59 deficiency LRG_41 |