| Protein category: |
Recombinant protein |
| Source: |
proteins, Recombinants or rec |
| Target: |
CDD45 / PTPRC Protein |
| Conjugation: |
histidine |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Group: |
recombinants |
| Gene target: |
His GST Tag), CD45 / PTPRC Protein (aa 453-1152 |
| Short name: |
His GST Tag), Recombinant Mouse CD45 / PTPRC Protein (aa 453-1152 |
| Technique: |
E, Tags, adv advises they will be reconstituted in a buffer soluion or culture medium for cell culture, coli recombinant proteins are , mouses, supplied as white sterile powder lyopillized, Recombinant, genetic recombinations , in Escherichia coli |
| Label: |
His |
| Species: |
Mouses, Mouse |
| Alternative name: |
C Protein (aa 453-1152, GST detection labelled), histidine &, receptor classification, recombinant Mouse CD45 / protein tyrosine phosphatase |
| Alternative technique: |
rec |
| Alternative to gene target: |
B220 and CD45 and CD45R and GP180 and L-CA and LCA and LY5 and T200, C, Cell surfaces, PTPRC and IDBG-105609 and ENSG00000081237 and 5788, PTPRC and IDBG-638670 and ENSBTAG00000023144 and 407152, Ptprc and IDBG-195821 and ENSMUSG00000026395 and 19264, heparan sulfate proteoglycan binding, receptor type, this GO :0000187 and activation of MAPK activity and biological process this GO :0001915 and negative regulation of T cell mediated cytotoxicity and biological process this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0001960 and negative regulation of cytokine-mediated signaling pathway and biological process this GO :0002244 and hematopoietic progenitor cell differentiation and biological process this GO :0002378 and immunoglobulin biosynthetic process and biological process this GO :0002711 and positive regulation of T cell mediated immunity and biological process this GO :0002923 and regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0002925 and positive regulation of humoral immune response mediated by circulating immunoglobulin and biological process this GO :0004725 and protein tyrosine phosphatase activity and molecular function this GO :0005001 and transmembrane receptor protein tyrosine phosphatase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006470 and protein dephosphorylation and biological process this GO :0006933 and negative regulation of cell adhesion involved in substrate-bound cell migration and biological process this GO :0007159 and leukocyte cell-cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007411 and axon guidance and biological process this GO :0008201 and heparin binding and molecular function this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010332 and response to gamma radiation and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016311 and dephosphorylation and biological process this GO :0016791 and phosphatase activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030183 and B cell differentiation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030890 and positive regulation of B cell proliferation and biological process this GO :0031953 and negative regulation of protein autophosphorylation and biological process this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0035335 and peptidyl-tyrosine dephosphorylation and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042100 and B cell proliferation and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0043395 and heparan sulfate proteoglycan binding and molecular function this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044770 and cell cycle phase transition and biological process this GO :0045059 and positive thymic T cell selection and biological process this GO :0045060 and negative thymic T cell selection and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045577 and regulation of B cell differentiation and biological process this GO :0045582 and positive regulation of T cell differentiation and biological process this GO :0045588 and positive regulation of gamma-delta T cell differentiation and biological process this GO :0045860 and positive regulation of protein kinase activity and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0048539 and bone marrow development and biological process this GO :0048864 and stem cell development and biological process this GO :0050732 and negative regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0050853 and B cell receptor signaling pathway and biological process this GO :0050855 and regulation of B cell receptor signaling pathway and biological process this GO :0050857 and positive regulation of antigen receptor-mediated signaling pathway and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051607 and defense response to virus and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071944 and cell periphery and cellular component this GO :2000473 and positive regulation of hematopoietic stem cell migration and biological process this GO :2000648 and positive regulation of stem cell proliferation and biological process this GO :2001236 and regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process, this GO :0004725 : protein tyrosine phosphatase activity, this GO :0004725 : protein tyrosine phosphatase activity and also this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity and also this GO :0005515 : protein binding and also this GO :0008201 : heparin binding and also this GO :0016791 : phosphatase activity and also this GO :0019901 : protein kinase binding and also this GO :0043395 : heparan sulfate proteoglycan binding, this GO :0005001 : transmembrane receptor protein tyrosine phosphatase activity, this GO :0005515 : protein binding, this GO :0008201 : heparin binding, this GO :0016791 : phosphatase activity, this GO :0019901 : protein kinase binding, this GO :0043395 : heparan sulfate proteoglycan binding, protein tyrosine phosphatase |
| Identity: |
9666 |
| Gene: |
PTPRC |
More about : PTPRC |
| Long gene name: |
protein tyrosine phosphatase, receptor type C |
| Synonyms gene: |
CD45 |
| Synonyms: |
LCA T200 GP180 |
| Locus: |
1q31, 1 , 3-q32 |
| Discovery year: |
1986-01-01 |
| GenBank acession: |
Y00062 |
| Entrez gene record: |
5788 |
| Pubmed identfication: |
2169617 |
| RefSeq identity: |
NM_002838 |
| Classification: |
Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type |
| Havana BLAST/BLAT: |
OTTHUMG00000035702 |
| Locus Specific Databases: |
PTPRCbase: Mutation registry for CD45 deficiency LRG_95 |