| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
OGG1 |
| Specificity: |
This antibody reacts specifically with OGG1 |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Subcellular locations: |
Nucleus |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human OGG1/8 hydroxyguanine DNA glycosylase |
| Gene ID: |
4968 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
All variants share the N-terminal region in common, Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, Aug 2008], Many alternative splice variants for this gene have been described, The action of this enzyme includes lyase activity for chain cleavage, Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8, [provided by RefSeq, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen, but the full-length nature for every variant has not been determined, depending on the last exon of the sequence, type 1 and type 2, which contains a mitochondrial targeting signal that is essential for mitochondrial localization, This gene encodes the enzyme responsible for the excision of 8-oxoguanine |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
HMMH HOGG1 OGH1 MUTM |
| Also known as: |
OGG1 Polyclonal Antibody |
| Other name: |
Anti-OGG1 Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
OGG1 |
| Short name: |
Anti-OGG1 (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-OGG1 (polyclonal) |
| Alternative technique: |
polyclonals |
| Identity: |
8125 |
| Gene: |
OGG1 |
More about : OGG1 |
| Long gene name: |
8-oxoguanine DNA glycosylase |
| Synonyms name: |
8-hydroxyguanine DNA glycosylase OGG1 type 1e OGG1 type 1d OGG1 type 1g OGG1 type 1h |
| Locus: |
3p25, 3 |
| Discovery year: |
1997-07-22 |
| GenBank acession: |
U96710 |
| Entrez gene record: |
4968 |
| Pubmed identfication: |
9207108 10449904 |
| RefSeq identity: |
NM_016821 |
| Classification: |
DNA glycosylases |
| Havana BLAST/BLAT: |
OTTHUMG00000097091 |