| Type: |
Conjugated Primary Antibody |
| Conjugated with: |
594, ALEXA FLUOR® |
| Host organism: |
Rabbit (Oryctolagus cuniculus) |
| Target Protein/Peptide: |
RRAD |
| Specificity: |
This antibody reacts specifically with RRAD |
| Modification: |
No modification has been applied to this antibody |
| Modification site: |
None |
| Clonality: |
Polyclonal Antibody |
| Clone: |
Polyclonal Antibodies |
| Concentration: |
1ug per 1ul |
| Antigen Source: |
KLH conjugated synthetic peptide derived from human RRAD |
| Gene ID: |
6236 |
| Applications: |
IF(IHC-P) |
| Applications with corresponding dilutions: |
IF(IHC-P)(1:50-200) |
| Cross reactive species: |
Mouse (Mus musculus), Rat (Rattus norvegicus), Human (Homo sapiens) |
| Cross Reactive Species details: |
However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species, No significant cross reactivity has been observed for this antibody for the tested species |
| Background information: |
Human Rad1 exhibits significant homology to Rad1 from S, It has also been shown to possess exonuclease activity, This complex is believed to be involved in cellular responses to DNA damage, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2 checkpoint activity, pombe, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C, Human Rad1 is a component of a heterotrimeric PCNA like complex that also contains the Rad9 and Hus1 proteins |
| Purification method: |
Purified by Protein A |
| Storage: |
50% glycerol and 0, Store at 4°, 09% sodium azide, C for 12 months, Water buffered solution containing 100ug/ml BSA |
| Excitation emission: |
590nm/617nm |
| Synonyms: |
REM3 RAD |
| Also known as: |
RRAD Polyclonal Antibody |
| Other name: |
Anti-RRAD Polyclonal |
| Advisory: |
For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, specificity and sensitivity, thus reducing its reactivity, Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody |
| Properties: |
For facs or microscopy Alexa 1 conjugate |
| Conjugation: |
Alexa Fluor |
| Group: |
Polyclonals and antibodies |
| About: |
The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target: |
RRAD |
| Short name: |
Anti-RRAD (Polyclonal) Fluor 594 |
| Technique: |
Pabs are a collection of immunoglobulin , Polyclonal antibodies , each identifying a different , whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Label: |
ALEXA |
| Alternative name: |
ALEXA Fluor 594, antibody to-Ras-related associated with diabetes (polyclonal) |
| Alternative technique: |
polyclonals |
| Alternative to gene target: |
GTP binding, Plasma membranes, RAD and RAD1 and REM3, RRAD and IDBG-35758 and ENSG00000166592 and 6236, RRAD and IDBG-633213 and ENSBTAG00000013929 and 505165, Rrad and IDBG-185875 and ENSMUSG00000031880 and 56437, this GO :0003924 and GTPase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005516 and calmodulin binding and molecular function this GO :0005525 and GTP binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006184 and GTP catabolic process and biological process this GO :0007165 and signal transduction and biological process this GO :0007264 and small GTPase mediated signal transduction and biological process this GO :0015031 and protein transport and biological process this GO :0016020 and membrane and cellular component, this GO :0003924 : GTPase activity, this GO :0003924 : GTPase activity and also this GO :0005515 : protein binding and also this GO :0005516 : calmodulin binding and also this GO :0005525 : GTP binding, this GO :0005515 : protein binding, this GO :0005516 : calmodulin binding, this GO :0005525 : GTP binding, Ras-related associated with diabetes |
| Identity: |
10446 |
| Gene: |
RRAD |
More about : RRAD |
| Long gene name: |
RRAD, Ras related glycolysis inhibitor and calcium channel regulator |
| Synonyms gene name: |
Ras related glycolysis inihibitor and calcium channel regulator , Ras-related associated with diabetes RRAD |
| Locus: |
16q22, 1 |
| Discovery year: |
1995-12-11 |
| GenBank acession: |
L24564 |
| Entrez gene record: |
6236 |
| Pubmed identfication: |
7859947 24992013 25114038 26546438 |
| RefSeq identity: |
NM_004165 |
| Classification: |
RGK type GTPase family |
| Havana BLAST/BLAT: |
OTTHUMG00000137511 |