| Category: |
Antibody |
| Concentration: |
2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form: |
Antigen affinity purified |
| Conjugation: |
Unconjugated |
| Clone: |
Polyclonal antibody |
| Recognised antigen: |
SOD3 Superoxide Dismutase 3 |
| Host animal: |
Rabbit (Oryctolagus cuniculus) |
| Clonality: |
Polyclonal (rabbit origin) |
| Species reactivity: |
Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications: |
ICC, IHC-F, IHC-P, WB |
| Recommended dilutions: |
5-1ug/ml, 5-1ug/ml, 5-1ug/ml, 5-1ug/ml, IHC (Frozen): 0, IHC (Paraffin): 0, Immunocytochemistry: 0, Western blot: 0 |
| Notes: |
Titration of the SOD3 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use: |
This SOD3 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot #: |
P08294 |
| Purity: |
Antigen affinity |
| Description: |
A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM, Hendrickson et al, SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen, Stern et al, The product of this gene is though to protect the brain, The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix(ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen, This gene encodes a member of the superoxide dismutase (SOD) protein family, and FISH, and other tissues from oxidative stress, linkage mapping, lungs, (1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids, (2003) narrowed the assignment to 4p15, 1 by somatic cell and radiation hybrid analysis, 3-p15, Superoxide Dismutase 3 is an enzyme that in humans is encoded by the SOD3 gene |
| Immunogen: |
An amino acid sequence from the N-terminus of human Superoxide Dismutase 3 (KVTEIWQEVMQRRDDD) was used as the immunogen for this SOD3 antibody |
| Storage: |
Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the SOD3 antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties: |
C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target: |
SOD3 Superoxide Dismutase 3 |
| Short name: |
SOD3 Antibody Superoxide Dismutase 3 |
| Technique: |
antibodies against human proteins, antibodies for, Antibody |
| Alternative name: |
SOD3 (Antibody to) Superoxide Dismutase 3 |
| Alternative technique: |
antibodies |
| Identity: |
11181 |
| Gene: |
SOD3 |
More about : SOD3 |
| Long gene name: |
superoxide dismutase 3 |
| Synonyms gene name: |
extracellular , superoxide dismutase 3 |
| Synonyms: |
EC-SOD |
| Locus: |
4p15, 2 |
| Discovery year: |
1988-05-08 |
| Entrez gene record: |
6649 |
| Havana BLAST/BLAT: |
OTTHUMG00000128565 |