| Also known as: |
CD8 |
| Other names: |
CD8 antigen, CD8a molecule, CD_antigen: CD8a, Leu2 T-lymphocyte antigen, OKT8 T-cell antigen, T cell co-receptor, T-cell antigen Leu2, T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, T-lymphocyte differentiation antigen T8/Leu-2, T8 T-cell antigen, alpha polypeptide (p32), T-cell surface glycoprotein CD8 alpha chain isoform 1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CD8 |
| Other gene names: |
CD8, CD8A, Leu2, MAL, MAL, p32, CD8A |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
RIV11 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, thymocytes and natural killer cells, The antibody RIV11 is directed against human CD8 and recognises all CD8 positive T-cells |
| Form/Appearance: |
02% sodium azide, 2 mg/ml purified monoclonal antibody in phosphated buffered saline (PBS) containing 50% glycerol + 0, 2% bovine serum albumin (BSA) + 0, Each vial contains 500 ul 0 |
| Storage and shipping: |
or in small aliquots the antibody should be stored at -20 degrees Celsius, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
ELISA (EIA), Immunocytochemistry (ICC), Immunohistochemistry (IHC-Frozen), Flow Cytometry (FC/FACS) |
| Description: |
This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity, Cytotoxic T cells cluster differentiators for flow cytometry |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
CD8 |
| Short name: |
Mouse Anti-CD8 |
| Technique: |
mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse antibody to-CD8 |
| Alternative technique: |
murine |
| Identity: |
1706 |
| Gene: |
CD8A |
More about : CD8A |
| Long gene name: |
CD8a molecule |
| Synonyms gene: |
CD8 |
| Synonyms gene name: |
CD8 antigen, alpha polypeptide (p32) T-cell surface glycoprotein CD8 alpha chain |
| Locus: |
2p11, 2 |
| Discovery year: |
1986-01-01 |
| Entrez gene record: |
925 |
| Pubmed identfication: |
1541829 |
| RefSeq identity: |
NM_001768 |
| Classification: |
CD molecules V-set domain containing |
| Havana BLAST/BLAT: |
OTTHUMG00000130265 |
| Locus Specific Databases: |
CD8Abase: Mutation registry for CD8 deficiency LRG_44 |