| Also known as: |
MT1 / CD43 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
MT1 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
B cells, CD43 may function as an adhesion molecule via interaction with CD54 although this has not been definitely established, In immunohistochemistry it reacts with T cells, It is used for the typing of lymphomas in paraffin sections, It may also inhibit leucocyte interactions with other cells, It may be used in the diagnosis of chronic lymphocytic leukemias (CLL), NK cells and monocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The antigen detected by MT1 is the only marker expressed on neoplasms of the very early precursor cells, The antigen is involved in the activation of T-cells, The membrane proximal portion of the cytoplasmic domain mediates an association with the cytoskeleton, This antibody is used to identify B cell lines and myeloma cells, This particular antibody might cross react with speacies outside of the listed ones, as an alternative to CD5, macrophages, myeloid cells and B cells (weak), Clone MT1 produces Mouse IgG1 immunoglobulins reactive with a 95-115 kD highly sialated glycoprotein |
| Form/Appearance: |
09% sodium azide, Each vial contains 100 ul 1 mg/ml purified monoclonal antibody in PBS containing 0 |
| Storage and shipping: |
or in small aliquots the antibody should be stored at -20 degrees Celsius, Store the antibody at +4 degrees Celsius |
| Tested applications:: |
Immunohistochemistry (IHC) (paraffin), Western Blot (WB), Immunohistochemistry (IHC) (frozen) |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
MT1 / CD43 |
| Short name: |
Mouse Anti-MT1 / CD43 |
| Technique: |
mouses, Mouse |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse antibody to-MT1 / CD43 |
| Alternative technique: |
murine |
| Identity: |
11249 |
| Gene: |
SPN |
More about : SPN |
| Long gene name: |
sialophorin |
| Synonyms gene name: |
CD43) , leukosialin, sialophorin (gpL115 |
| Synonyms: |
LSN CD43 GPL115 |
| Synonyms name: |
leukosialin |
| Locus: |
16p11, 2 |
| Discovery year: |
1988-08-31 |
| GenBank acession: |
J04536 |
| Pubmed identfication: |
2784859 2521952 |
| Classification: |
CD molecules |
| Havana BLAST/BLAT: |
OTTHUMG00000097765 |