| Also known as: |
CDK4 |
| Other names: |
Cell division protein kinase 4, Cyclin-dependent kinase 4, PSK-J3, cell division protein kinase 4, cyclin-dependent kinase 4, cyclin-dependent kinase 4, cyclin-dependent kinase 4 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CDK4 |
| Gene name synonims: |
PSK-J3, CMM3 |
| Other gene names: |
CDK4, CMM3, N/A, PSK-J3, CDK4 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
3F9-B12-C8 |
| Host organism: |
Mouse (Mus musculus) |
| Source organism: |
Human (Homo sapiens) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Mouse (Mus musculus), Rat (Rattus norvegicus), the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens) |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, This antibody detects endogenous levels of CDK4 and does not cross-react with related proteins |
| Purification method: |
Affinity purified |
| Form/Appearance: |
150 mM NaCl) with 0, 50%, Purified mouse monoclonal in buffer containing 0, 1M Tris-Glycine (pH 7, 2% sodium azide, 4, Liquid, glycerol |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
Cycles of freezing and thawing may denaturate the polypeptide chains of the antibodies and reduce their activity and should be avoided, the antibody should be aliquoted and kept at -20 degrees Celsius, For optimal long term storage |
| Tested applications:: |
Western Blot (WB) |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| French translation: |
anticorps |
| Gene target: |
monoclonal CDK4 |
| Short name: |
Mouse monoclonal CDK4 antibody |
| Technique: |
mouse monoclonals, mouses, Mouse monoclonal |
| Host: |
Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG |
| Species: |
Mouses, Mouse |
| Alternative name: |
Mouse monoclonal cyclin-dependent kinase 4 (Antibody to) |
| Alternative technique: |
murine |
| Alternative to gene target: |
CDK4 and IDBG-43642 and ENSG00000135446 and 1019, CMM3 and PSK-J3, Cdk4 and IDBG-194056 and ENSMUSG00000006728 and 102641469, nuclei, this GO :0000082 and G1/S transition of mitotic cell cycle and biological process this GO :0000278 and mitotic cell cycle and biological process this GO :0000307 and cyclin-dependent protein kinase holoenzyme complex and cellular component this GO :0000785 and chromatin and cellular component this GO :0002088 and lens development in camera-type eye and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004693 and cyclin-dependent protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005730 and nucleolus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005923 and tight junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007165 and signal transduction and biological process this GO :0007623 and circadian rhythm and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0009636 and response to toxic substance and biological process this GO :0010033 and response to organic substance and biological process this GO :0010288 and response to lead ion and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010971 and positive regulation of G2/M transition of mitotic cell cycle and biological process this GO :0016301 and kinase activity and molecular function this GO :0016772 and transferase activity, this GO :0004672 : protein kinase activity, this GO :0004672 : protein kinase activity and also this GO :0004674 : protein serine/threonine kinase activity and also this GO :0004693 : cyclin-dependent protein serine/threonine kinase activity and also this GO :0004713 : protein tyrosine kinase activity and also this GO :0005515 : protein binding and also this GO :0005524 : ATP binding and also this GO :0016301 : kinase activity and also this GO :0016772 : transferase activity, this GO :0004674 : protein serine/threonine kinase activity, this GO :0004693 : cyclin-dependent protein serine/threonine kinase activity, this GO :0004713 : protein tyrosine kinase activity, this GO :0005515 : protein binding, this GO :0005524 : ATP binding, this GO :0016301 : kinase activity, this GO :0016772 : transferase activity, this GO :0030332 : cyclin binding, this GO :0032403 : protein complex binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0030332 : cyclin binding and also this GO :0032403 : protein complex binding, transferring phosphorus-containing groups and molecular function this GO :0030332 and cyclin binding and molecular function this GO :0031100 and organ regeneration and biological process this GO :0031965 and nuclear membrane and cellular component this GO :0032403 and protein complex binding and molecular function this GO :0033574 and response to testosterone and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042493 and response to drug and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045727 and positive regulation of translation and biological process this GO :0045793 and positive regulation of cell size and biological process this GO :0048146 and positive regulation of fibroblast proliferation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0051301 and cell division and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0055093 and response to hyperoxia and biological process this GO :0071157 and negative regulation of cell cycle arrest and biological process, 12567, cyclin-dependent kinase 4 |
| Identity: |
1773 |
| Gene: |
CDK4 |
More about : CDK4 |
| Long gene name: |
cyclin dependent kinase 4 |
| Synonyms: |
PSK-J3 |
| Locus: |
12q14, 1 |
| Discovery year: |
1993-07-28 |
| GenBank acession: |
M14505 |
| Entrez gene record: |
1019 |
| Pubmed identfication: |
8275715 |
| RefSeq identity: |
NM_000075 |
| Classification: |
Cyclin dependent kinases |
| Havana BLAST/BLAT: |
OTTHUMG00000170382 |
| Locus Specific Databases: |
LRG_490 |