| Also known as: |
CTNNB1 / Beta Catenin |
| Other names: |
88kDa, Beta-catenin, Catenin beta-1, beta 1, catenin (cadherin-associated protein), catenin beta-1, catenin beta-1 |
| Category: |
Antibodies |
| Subcategory: |
Mnoclonal antibodies |
| Gene name: |
CTNNB1 |
| Other gene names: |
CTNNB, CTNNB, CTNNB1, MRD19, armadillo, CTNNB1 |
| Clonality: |
Monoclonal |
| Immunoglobulin isotype: |
IgG1 |
| Clone: |
EM-22 |
| Host organism: |
Mouse (Mus musculus) |
| Species reactivity: |
Due to limited knowledge and inability for testing each and every species, Human (Homo sapiens), Mouse (Mus musculus), the reactivity of the antibody may extend to other species which are not listed hereby, Hamster |
| Specificity and cross-reactivity: |
Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, an 88 kD multifunctional protein involved both in cell adhesion and in activation of transcription, The antibody EM-22 reacts with C-terminal part of beta-catenin |
| Purification method: |
Protein A Purified |
| Form/Appearance: |
15 mM sodium azide, pH 7, 4, PBS |
| Concentration: |
1 miligram per 1 mililiter |
| Storage and shipping: |
For long term storage aliquot and keep the antibody at -20 degrees Celsius, Freeze-thaw cycles should be avoided in order to retain the activity of the antibody, Store at +4 degrees Celsius for short term storage |
| Tested applications:: |
Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Properties: |
Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS mono they should be stored frozen at - 24°, humans , ssp |
| About: |
Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test: |
A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name: |
Mus musculus |
| Gene target: |
Monoclonal [ EM-22] (IgG1) CTNNB1 / Beta Catenin |
| Short name: |
Mouse Monoclonal [clone EM-22] (IgG1) CTNNB1 / Beta Catenin Antibody |
| Technique: |
Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype: |
IgG1 |
| Species: |
Humans, Mouses, Human |
| Alternative name: |
88kDa / b Catenin (Antibody to), b 1, sapiens catenin (cadherin-associated protein), Mouse monoclonal [clonality EM-22] (IgG1) to H |
| Alternative technique: |
antibodies |
| Alternative to gene target: |
88kDa, CTNNB1 and IDBG-27347 and ENSG00000168036 and 1499, CTNNB1 and IDBG-644470 and ENSBTAG00000016420 and 539003, Ctnnb1 and IDBG-205243 and ENSMUSG00000006932 and 12387, DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007016 and cytoskeletal anchoring at plasma membrane and biological process this GO :0007155 and cell adhesion and biological process this GO :0007160 and cell-matrix adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007398 and ectoderm development and biological process this GO :0007403 and glial cell fate determination and biological process this GO :0007494 and midgut development and biological process this GO :0007507 and heart development and biological process this GO :0008022 and protein C-terminus binding and molecular function this GO :0008134 and transcription factor binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009725 and response to hormone and biological process this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0009948 and anterior/posterior axis specification and biological process this GO :0009950 and dorsal/ventral axis specification and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0009987 and cellular process and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0010718 and positive regulation of epithelial to mesenchymal transition and biological process this GO :0010909 and positive regulation of heparan sulfate proteoglycan biosynthetic process and biological process this GO :0014010 and Schwann cell proliferation and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0014704 and intercalated disc and cellular component this GO :0016020 and membrane and cellular component this GO :0016055 and Wnt signaling pathway and biological process this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016328 and lateral plasma membrane and cellular component this GO :0016331 and morphogenesis of embryonic epithelium and biological process this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0016342 and catenin complex and cellular component this GO :0019899 and enzyme binding and molecular function this GO :0019900 and kinase binding and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0021819 and layer formation in cerebral cortex and biological process this GO :0022009 and central nervous system vasculogenesis and biological process this GO :0022405 and hair cycle process and biological process this GO :0030018 and Z disc and cellular component this GO :0030027 and lamellipodium and cellular component this GO :0030054 and cell junction and cellular component this GO :0030057 and desmosome and cellular component this GO :0030097 and hemopoiesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0030217 and T cell differentiation and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030326 and embryonic limb morphogenesis and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0030521 and androgen receptor signaling pathway and biological process this GO :0030539 and male genitalia development and biological process this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030877 and beta-catenin destruction complex and cellular component this GO :0030900 and forebrain development and biological process this GO :0030902 and hindbrain development and biological process this GO :0030997 and regulation of centriole-centriole cohesion and biological process this GO :0031016 and pancreas development and biological process this GO :0031069 and hair follicle morphogenesis and biological process this GO :0031253 and cell projection membrane and cellular component this GO :0031528 and microvillus membrane and cellular component this GO :0031641 and regulation of myelination and biological process this GO :0032331 and negative regulation of chondrocyte differentiation and biological process this GO :0032355 and response to estradiol and biological process this GO :0032403 and protein complex binding and molecular function this GO :0032481 and positive regulation of type I interferon production and biological process this GO :0032993 and protein-DNA complex and cellular component this GO :0033077 and T cell differentiation in thymus and biological process this GO :0033234 and negative regulation of protein sumoylation and biological process this GO :0034097 and response to cytokine and biological process this GO :0034333 and adherens junction assembly and biological process this GO :0034394 and protein localization to cell surface and biological process this GO :0034613 and cellular protein localization and biological process this GO :0034750 and Scrib-APC-beta-catenin complex and cellular component this GO :0035050 and embryonic heart tube development and biological process this GO :0035112 and genitalia morphogenesis and biological process this GO :0035115 and embryonic forelimb morphogenesis and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0035255 and ionotropic glutamate receptor binding and molecular function this GO :0035257 and nuclear hormone receptor binding and molecular function this GO :0035315 and hair cell differentiation and biological process this GO :0036023 and embryonic skeletal limb joint morphogenesis and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042129 and regulation of T cell proliferation and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042493 and response to drug and biological process this GO :0042692 and muscle cell differentiation and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043005 and neuron projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043123 and positive regulation of I-kappaB kinase/NF-kappaB signaling and biological process this GO :0043198 and dendritic shaft and cellular component this GO :0043234 and protein complex and cellular component this GO :0043296 and apical junction complex and cellular component this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0043587 and tongue morphogenesis and biological process this GO :0043588 and skin development and biological process this GO :0043627 and response to estrogen and biological process this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0044325 and ion channel binding and molecular function this GO :0044334 and canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition and biological process this GO :0044336 and canonical Wnt signaling pathway involved in negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045177 and apical part of cell and cellular component this GO :0045202 and synapse and cellular component this GO :0045294 and alpha-catenin binding and molecular function this GO :0045296 and cadherin binding and molecular function this GO :0045445 and myoblast differentiation and biological process this GO :0045453 and bone resorption and biological process this GO :0045595 and regulation of cell differentiation and biological process this GO :0045596 and negative regulation of cell differentiation and biological process this GO :0045603 and positive regulation of endothelial cell differentiation and biological process this GO :0045667 and regulation of osteoblast differentiation and biological process this GO :0045669 and positive regulation of osteoblast differentiation and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045671 and negative regulation of osteoclast differentiation and biological process this GO :0045743 and positive regulation of fibroblast growth factor receptor signaling pathway and biological process this GO :0045765 and regulation of angiogenesis and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046332 and SMAD binding and molecular function this GO :0046686 and response to cadmium ion and biological process this GO :0048145 and regulation of fibroblast proliferation and biological process this GO :0048262 and determination of dorsal/ventral asymmetry and biological process this GO :0048469 and cell maturation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0048489 and synaptic vesicle transport and biological process this GO :0048513 and organ development and biological process this GO :0048538 and thymus development and biological process this GO :0048599 and oocyte development and biological process this GO :0048617 and embryonic foregut morphogenesis and biological process this GO :0048660 and regulation of smooth muscle cell proliferation and biological process this GO :0048715 and negative regulation of oli this GO dendrocyte differentiation and biological process this GO :0050681 and androgen receptor binding and molecular function this GO :0050808 and synapse organization and biological process this GO :0050998 and nitric-oxide synthase binding and molecular function this GO :0051145 and smooth muscle cell differentiation and biological process this GO :0051149 and positive regulation of muscle cell differentiation and biological process this GO :0051291 and protein heterooli this GO merization and biological process this GO :0060066 and oviduct development and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060173 and limb development and biological process this GO :0060439 and trachea morphogenesis and biological process this GO :0060440 and trachea formation and biological process this GO :0060441 and epithelial tube branching involved in lung morphogenesis and biological process this GO :0060479 and lung cell differentiation and biological process this GO :0060484 and lung-associated mesenchyme development and biological process this GO :0060492 and lung induction and biological process this GO :0060742 and epithelial cell differentiation involved in prostate gland development and biological process this GO :0060769 and positive regulation of epithelial cell proliferation involved in prostate gland development and biological process this GO :0060789 and hair follicle placode formation and biological process this GO :0060916 and mesenchymal cell proliferation involved in lung development and biological process this GO :0061047 and positive regulation of branching involved in lung morphogenesis and biological process this GO :0061154 and endothelial tube morphogenesis and biological process this GO :0061198 and fungiform papilla formation and biological process this GO :0061324 and canonical Wnt receptor signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070369 and beta-catenin-TCF7L2 complex and cellular component this GO :0070411 and I-SMAD binding and molecular function this GO :0070412 and R-SMAD binding and molecular function this GO :0070491 and repressing transcription factor binding and molecular function this GO :0070602 and regulation of centromeric sister chromatid cohesion and biological process this GO :0071260 and cellular response to mechanical stimulus and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0071664 and catenin-TCF7L2 complex and cellular component this GO :0071681 and cellular response to indole-3-methanol and biological process this GO :0071944 and cell periphery and cellular component this GO :0072001 and renal system development and biological process this GO :0072033 and renal vesicle formation and biological process this GO :0072053 and renal inner medulla development and biological process this GO :0072054 and renal outer medulla development and biological process this GO :0072079 and nephron tubule formation and biological process this GO :0072182 and regulation of nephron tubule epithelial cell differentiation and biological process this GO :0090279 and regulation of calcium ion import and biological process this GO :1901215 and negative regulation of neuron death and biological process this GO :1990314 and cellular response to insulin-like growth factor stimulus and biological process this GO :2000008 and regulation of protein localization to cell surface and biological process this GO :2000017 and positive regulation of determination of dorsal identity and biological process this GO :2001234 and negative regulation of apoptotic signaling pathway and biological process, armadillo and CTNNB and MRD19, beta 1, nuclei, repressing transcription factor binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0000578 and embryonic axis specification and biological process this GO :0000904 and cell morphogenesis involved in differentiation and biological process this GO :0000922 and spindle pole and cellular component this GO :0001102 and RNA polymerase II activating transcription factor binding and molecular function this GO :0001501 and skeletal system development and biological process this GO :0001569 and patterning of blood vessels and biological process this GO :0001570 and vasculogenesis and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001702 and gastrulation with mouth forming second and biological process this GO :0001706 and endoderm formation and biological process this GO :0001708 and cell fate specification and biological process this GO :0001709 and cell fate determination and biological process this GO :0001711 and endodermal cell fate commitment and biological process this GO :0001764 and neuron migration and biological process this GO :0001822 and kidney development and biological process this GO :0001837 and epithelial to mesenchymal transition and biological process this GO :0001840 and neural plate development and biological process this GO :0001889 and liver development and biological process this GO :0002052 and positive regulation of neuroblast proliferation and biological process this GO :0002053 and positive regulation of mesenchymal cell proliferation and biological process this GO :0002089 and lens morphogenesis in camera-type eye and biological process this GO :0003136 and negative regulation of heart induction by canonical Wnt receptor signaling pathway and biological process this GO :0003266 and regulation of secondary heart field cardioblast proliferation and biological process this GO :0003337 and mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0003338 and metanephros morphogenesis and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003690 and double-stranded DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003713 and transcription coactivator activity and molecular function this GO :0004871 and signal transducer activity and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005654 and nucleoplasm and cellular component this GO :0005667 and transcription factor complex and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005912 and adherens junction and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005915 and zonula adherens and cellular component this GO :0005916 and fascia adherens and cellular component this GO :0005923 and tight junction and cellular component this GO :0005938 and cell cortex and cellular component this GO :0006351 and transcription, this GO :0001102 : RNA polymerase II activating transcription factor binding, this GO :0001102 : RNA polymerase II activating transcription factor binding and also this GO :0003677 : DNA binding and also this GO :0003682 : chromatin binding and also this GO :0003690 : double-stranded DNA binding and also this GO :0003700 : sequence-specific DNA binding transcription factor activity and also this GO :0003713 : transcription coactivator activity and also this GO :0004871 : signal transducer activity and also this GO :0005198 : structural molecule activity and also this GO :0005488 : binding and also this GO :0005515 : protein binding and also this GO :0008022 : protein C-terminus binding and also this GO :0008134 : transcription factor binding and also this GO :0019899 : enzyme binding and also this GO :0019900 : kinase binding and also this GO :0019901 : protein kinase binding and also this GO :0019903 : protein phosphatase binding and also this GO :0030331 : estrogen receptor binding and also this GO :0032403 : protein complex binding and also this GO :0035255 : ionotropic glutamate receptor binding and also this GO :0035257 : nuclear hormone receptor binding and also this GO :0044212 : transcription regulatory region DNA binding and also this GO :0044325 : ion channel binding and also this GO :0045294 : alpha-catenin binding and also this GO :0045296 : cadherin binding and also this GO :0046332 : SMAD binding and also this GO :0050681 : androgen receptor binding and also this GO :0050998 : nitric-oxide synthase binding and also this GO :0070411 : I-SMAD binding and also this GO :0070412 : R-SMAD binding and also this GO :0070491 : repressing transcription factor binding, this GO :0003677 : DNA binding, this GO :0003682 : chromatin binding, this GO :0003690 : double-stranded DNA binding, this GO :0003700 : sequence-specific DNA binding transcription factor activity, this GO :0003713 : transcription coactivator activity, this GO :0004871 : signal transducer activity, this GO :0005198 : structural molecule activity, this GO :0005488 : binding, this GO :0005515 : protein binding, this GO :0008022 : protein C-terminus binding, this GO :0008134 : transcription factor binding, this GO :0019899 : enzyme binding, this GO :0019900 : kinase binding, this GO :0019901 : protein kinase binding, this GO :0019903 : protein phosphatase binding, this GO :0030331 : estrogen receptor binding, this GO :0032403 : protein complex binding, this GO :0035255 : ionotropic glutamate receptor binding, this GO :0035257 : nuclear hormone receptor binding, this GO :0044212 : transcription regulatory region DNA binding, this GO :0044325 : ion channel binding, this GO :0045294 : alpha-catenin binding, this GO :0045296 : cadherin binding, this GO :0046332 : SMAD binding, this GO :0050681 : androgen receptor binding, this GO :0050998 : nitric-oxide synthase binding, this GO :0070411 : I-SMAD binding, this GO :0070412 : R-SMAD binding, this GO :0070491 : repressing transcription factor binding, catenin (cadherin-associated protein) |
| Identity: |
2514 |
| Gene: |
CTNNB1 |
More about : CTNNB1 |
| Long gene name: |
catenin beta 1 |
| Synonyms gene: |
CTNNB |
| Synonyms gene name: |
88kDa catenin (cadherin-associated protein), beta 1, beta 1 , beta 1 (88kD) catenin (cadherin-associated protein), catenin (cadherin-associated protein) |
| Synonyms: |
beta-catenin armadillo |
| Locus: |
3p22, 1 |
| Discovery year: |
1993-07-13 |
| GenBank acession: |
X87838 |
| Entrez gene record: |
1499 |
| Pubmed identfication: |
7829088 |
| RefSeq identity: |
NM_001098210 |
| Classification: |
NineTeen complex Armadillo repeat containing |
| Havana BLAST/BLAT: |
OTTHUMG00000131393 |
| Locus Specific Databases: |
LRG_1108 |